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Random-access wide-field mesoscopy for centimetre-scale imaging of biodynamics with subcellular resolution
Random-access wide-field mesoscopy enables the imaging of in vivo biodynamics in mice over an area of 160 mm2 and at a subcellular spatial resolution of about 2 μm.
- Ruheng Shi
- , Xinyue Chen
- & Lingjie Kong
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Article |
A diamond voltage imaging microscope
Nitrogen-vacancy centres in surface-engineered diamond are demonstrated to operate as charge-sensitive fluorescent reporters, enabling an optical scheme for voltage recording in physical and biological systems.
- D. J. McCloskey
- , N. Dontschuk
- & D. A. Simpson
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News & Views |
Video-rate gigapixel imaging of the brain
A wide-field system that can perform video-rate imaging of the entire area of the brain of an awake mouse is aiding the study of neurones, epilepsy and the immune system.
- Gail McConnell
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Article |
Video-rate imaging of biological dynamics at centimetre scale and micrometre resolution
Video-rate imaging of the brains of awake mice with a field of view of 10 × 12 mm2 and a spatial resolution of 1.2 µm is accomplished.
- Jingtao Fan
- , Jinli Suo
- & Qionghai Dai
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Article |
Combined multi-plane phase retrieval and super-resolution optical fluctuation imaging for 4D cell microscopy
By combining the sensitivity and high temporal resolution of phase imaging with the specificity and high spatial resolution of fluorescence microscopy, a 4D microscope is demonstrated that visualizes in three dimensions the fast cellular processes in living cells at up to 200 Hz.
- A. Descloux
- , K. S. Grußmayer
- & T. Lasser
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Letter |
Super-resolution imaging of multiple cells by optimized flat-field epi-illumination
An epi-illumination system based on microlens arrays enables field-independent imaging of multiple cells with nanoscale resolution and large field of views.
- Kyle M. Douglass
- , Christian Sieben
- & Suliana Manley
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Letter |
Removing orientation-induced localization biases in single-molecule microscopy using a broadband metasurface mask
A custom-designed metamaterial mask helps improve the accuracy of microscopy of single fluorescent molecules.
- Mikael P. Backlund
- , Amir Arbabi
- & W. E. Moerner
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Super-resolved snapshot hyperspectral imaging of solid-state quantum emitters for high-throughput integrated quantum technologies
Improved time resolution