Supramolecular chemistry

Supramolecular chemistry is the study of entities of greater complexity than individual molecules — assemblies of molecules that bond and organize through intermolecular interactions. The design and synthesis of supramolecular systems invokes interactions beyond the covalent bond, using, for example, hydrogen bonding, metal coordination and π interactions to bring discrete building blocks together.


Latest Research and Reviews

News and Comment

  • News and Views |

    In biological systems, order typically emerges from out-of-equilibrium molecular processes that control both static patterns and dynamic changes. Now, the self-regulating assembly and disassembly of a synthetic system has been achieved on the micrometre scale, by coupling the growth of a DNA nanotube to a biochemical oscillator.

    • Tim Liedl
    Nature Chemistry 11, 497-499
  • News and Views |

    The structure of self-assembled aggregates depends critically on the manner in which the building blocks organize themselves. Now, such a self-assembly process has been monitored in situ using liquid-phase transmission electron microscopy, unveiling a new pathway of vesicle formation.

    • Arash Nikoubashman
    •  & Friederike Schmid
    Nature Chemistry 11, 298-300
  • Research Highlights |

    New experiments on swarms of Caenorhabditis elegans reveal that the worm can form a dynamical network that can be understood using active matter physics, and controlled using genetic manipulation.

    • Zoe Budrikis
  • Research Highlights |

    Metal–organic frameworks with certain compositions can exist as glasses. Processable materials featuring intrinsic porosity are rare and are expected to be invaluable in chemical separations.

    • Andrew Bissette