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QR-1011 restores defective ABCA4 splicing caused by multiple severe ABCA4 variants underlying Stargardt disease
- Melita Kaltak
- , Petra de Bruijn
- & Jim Swildens
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Prediction of alternative pre-mRNA splicing outcomes
- Rayan Najjar
- & Tomas Mustelin
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Diet-induced rewiring of the Wnt gene regulatory network connects aberrant splicing to fatty liver and liver cancer in DIAMOND mice
- Ana López-Pérez
- , Silvia Remeseiro
- & Andreas Hörnblad
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Differential exon usage of developmental genes is associated with deregulated epigenetic marks
- Hoang Thu Trang Do
- , Siba Shanak
- & Volkhard Helms
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| Open Access
Analysis of the impact of DGAT1 p.M435L and p.K232A variants on pre-mRNA splicing in a full-length gene assay
- Nicolas Gaiani
- , Lorraine Bourgeois-Brunel
- & Arnaud Boulling
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Low-grade glioma risk SNP rs11706832 is associated with type I interferon response pathway genes in cell lines
- Adam Rosenbaum
- , Anna M. Dahlin
- & Beatrice Melin
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Alternative splicing of the SUMO1/2/3 transcripts affects cellular SUMOylation and produces functionally distinct SUMO protein isoforms
- Myriah L. Acuña
- , Andrea García-Morin
- & Germán Rosas-Acosta
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Quantitative magnetic resonance imaging assessment of muscle composition in myotonic dystrophy mice
- Ariadna Bargiela
- , Amadeo Ten-Esteve
- & Ruben Artero
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Deep RNA sequencing of intensive care unit patients with COVID-19
- Alger M. Fredericks
- , Maximilian S. Jentzsch
- & Sean F. Monaghan
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Exploring the mechanistic link between SF3B1 mutation and ring sideroblast formation in myelodysplastic syndrome
- Tetsuro Ochi
- , Tohru Fujiwara
- & Hideo Harigae
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PCBP1 is associated with rheumatoid arthritis by affecting RNA products of genes involved in immune response in Th1 cells
- Xue Cao
- , Panlong Li
- & Yanwei Cheng
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Article
| Open AccessExpression ratio of circular to linear ANRIL in hypertensive patients with coronary artery disease
- Iman Razeghian-Jahromi
- , Mohammad Javad Zibaeenezhad
- & Mahintaj Dara
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Restrained expression of canine glucocorticoid receptor splice variants α and P prognosticates fatal disease outcome in SIRS
- Brigitta Margit Kállai
- , Judit Csöndes
- & Tamás Mészáros
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Machine learning random forest for predicting oncosomatic variant NGS analysis
- Eric Pellegrino
- , Coralie Jacques
- & L’Houcine Ouafik
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Identification of splice regulators of fibronectin-EIIIA and EIIIB by direct measurement of exon usage in a flow-cytometry based CRISPR screen
- Jessica A. Hensel
- , Brent D. Heineman
- & Patrick A. Murphy
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Induction of cryptic pre-mRNA splice-switching by antisense oligonucleotides
- Kristin A. Ham
- , Niall P. Keegan
- & Steve D. Wilton
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Improved methods for RNAseq-based alternative splicing analysis
- Rebecca F. Halperin
- , Apurva Hegde
- & Nicholas J. Schork
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A novel tissue specific alternative splicing variant mitigates phenotypes in Ets2 frame-shift mutant models
- Yuki Kishimoto
- , Iori Nishiura
- & Ayako Isotani
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CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer
- Simon Uzor
- , Sean R. Porazinski
- & Michael R. Ladomery
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Disruption of pathways regulated by Integrator complex in Galloway–Mowat syndrome due to WDR73 mutations
- F. C. Tilley
- , C. Arrondel
- & G. Mollet
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Single-cell differential splicing analysis reveals high heterogeneity of liver tumor-infiltrating T cells
- Shang Liu
- , Biaofeng Zhou
- & Shiping Liu
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Using antisense oligonucleotides for the physiological modulation of the alternative splicing of NF1 exon 23a during PC12 neuronal differentiation
- Josep Biayna
- , Helena Mazuelas
- & Eduard Serra
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Cir-ITCH inhibits gastric cancer migration, invasion and proliferation by regulating the Wnt/β-catenin pathway
- Yang Peng
- & Hong Hong Wang
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Pathogenic impact of transcript isoform switching in 1,209 cancer samples covering 27 cancer types using an isoform-specific interaction network
- Abdullah Kahraman
- , Tülay Karakulak
- & Christian von Mering
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The integral spliceosomal component CWC15 is required for development in Arabidopsis
- Daniel Slane
- , Cameron H. Lee
- & Gerd Jürgens
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Genomic analyses of early responses to radiation in glioblastoma reveal new alterations at transcription, splicing, and translation levels
- Saket Choudhary
- , Suzanne C. Burns
- & Luiz O. Penalva
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Splicing- and demethylase-independent functions of LSD1 in zebrafish primitive hematopoiesis
- Junya Tamaoki
- , Miki Takeuchi
- & Makoto Kobayashi
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| Open Access
Shared and Independent Genetic Basis of Resistance to Bt Toxin Cry2Ab in Two Strains of Pink Bollworm
- Jeffrey A. Fabrick
- , Dannialle M. LeRoy
- & Bruce E. Tabashnik
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Complex intron generation in the yeast genus Lipomyces
- Norbert Ág
- , Napsugár Kavalecz
- & Erzsébet Fekete
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| Open Access
Acute thiamethoxam toxicity in honeybees is not enhanced by common fungicide and herbicide and lacks stress-induced changes in mRNA splicing
- Pâmela Decio
- , Pinar Ustaoglu
- & Matthias Soller
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Classes of non-conventional tetraspanins defined by alternative splicing
- Nikolas Hochheimer
- , Ricarda Sies
- & Thorsten Lang
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| Open Access
Reduction of integrin alpha 4 activity through splice modulating antisense oligonucleotides
- May T. Aung-Htut
- , Iain Comerford
- & Steve D. Wilton
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| Open Access
The Single-molecule long-read sequencing of Scylla paramamosain
- Haifu Wan
- , Xiwei Jia
- & Yilei Wang
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A spliceosomal twin intron (stwintron) participates in both exon skipping and evolutionary exon loss
- Napsugár Kavalecz
- , Norbert Ág
- & Erzsébet Fekete
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| Open Access
Co-regulated gene expression of splicing factors as drivers of cancer progression
- Esmee Koedoot
- , Marcel Smid
- & Bob van de Water
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| Open Access
The germ cell marker dead end reveals alternatively spliced transcripts with dissimilar expression
- Ana Carina Nogueira Vasconcelos
- , Danilo Pedro Streit Jr.
- & Goro Yoshizaki
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Efficient system for upstream mRNA trans-splicing to generate covalent, head-to-tail, protein multimers
- Hiroaki Mitsuhashi
- , Sachiko Homma
- & Jeffrey Boone Miller
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| Open Access
Insights into the biogenesis and potential functions of exonic circular RNA
- Chikako Ragan
- , Gregory J. Goodall
- & Thomas Preiss
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| Open Access
Somatic alterations compromised molecular diagnosis of DOCK8 hyper-IgE syndrome caused by a novel intronic splice site mutation
- Beate Hagl
- , Benedikt D. Spielberger
- & Ellen D. Renner
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| Open Access
The m6A-methylase complex recruits TREX and regulates mRNA export
- Simon Lesbirel
- , Nicolas Viphakone
- & Stuart A. Wilson
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AAV9-mediated Rbm24 overexpression induces fibrosis in the mouse heart
- Maarten M. G. van den Hoogenhof
- , Ingeborg van der Made
- & Esther E. Creemers
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Phosphorylation of the RSRSP stretch is critical for splicing regulation by RNA-Binding Motif Protein 20 (RBM20) through nuclear localization
- Rie Murayama
- , Mariko Kimura-Asami
- & Hidehito Kuroyanagi
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DNAJC17 is localized in nuclear speckles and interacts with splicing machinery components
- A. Pascarella
- , G. Ferrandino
- & E. Amendola
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A role for SOX9 in post-transcriptional processes: insights from the amphibian oocyte
- M. Penrad-Mobayed
- , C. Perrin
- & R. A. Veitia
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| Open Access
Small nuclear RNA-mediated modulation of splicing reveals a therapeutic strategy for a TREM2 mutation and its post-transcriptional regulation
- Motoaki Yanaizu
- , Kenji Sakai
- & Jun-ichi Satoh
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SpliceDetector: a software for detection of alternative splicing events in human and model organisms directly from transcript IDs
- Mandana Baharlou Houreh
- , Payam Ghorbani Kalkhajeh
- & Esmaeil Ebrahimie
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Complementarity of assembly-first and mapping-first approaches for alternative splicing annotation and differential analysis from RNAseq data
- Clara Benoit-Pilven
- , Camille Marchet
- & Vincent Lacroix
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The SR protein B52/SRp55 regulates splicing of the period thermosensitive intron and mid-day siesta in Drosophila
- Zhichao Zhang
- , Weihuan Cao
- & Isaac Edery
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Cardiac glycoside/aglycones inhibit HIV-1 gene expression by a mechanism requiring MEK1/2-ERK1/2 signaling
- Raymond W. Wong
- , Clifford A. Lingwood
- & Alan Cochrane
Dysregulation of RNA splicing in early non-alcoholic fatty liver disease through hepatocellular carcinoma