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| Open AccessPeriostin contributes to the maturation and shape retention of tissue-engineered cartilage
- Ryoko Inaki
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- & Kazuto Hoshi
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| Open AccessThe tomato subtilase family includes several cell death-related proteinases with caspase specificity
- Sven Reichardt
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| Open AccessGranzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction
- Valerio Russo
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| Open AccessAttenuation of autophagy impacts on muscle fibre development, starvation induced stress and fibre regeneration following acute injury
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| Open AccessInhibitory effects of Myricetin derivatives on curli-dependent biofilm formation in Escherichia coli
- Ken-ichi Arita-Morioka
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| Open AccessExpression and Regulation of Deubiquitinase-Resistant, Unanchored Ubiquitin Chains in Drosophila
- Jessica R. Blount
- , Kozeta Libohova
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| Open AccessThe conserved RNA recognition motif and C3H1 domain of the Not4 ubiquitin ligase regulate in vivo ligase function
- Hongfeng Chen
- , Tirupataiah Sirupangi
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| Open AccessMolecular mechanism of ER stress-induced pre-emptive quality control involving association of the translocon, Derlin-1, and HRD1
- Hisae Kadowaki
- , Pasjan Satrimafitrah
- & Hideki Nishitoh
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| Open AccessDefective immuno- and thymoproteasome assembly causes severe immunodeficiency
- Irina Treise
- , Eva M. Huber
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| Open AccessPhotoreceptor-induced RPE phagolysosomal maturation defects in Stargardt-like Maculopathy (STGD3)
- Camille Dejos
- , Sharee Kuny
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| Open AccessProteolysis inhibition by hibernating bear serum leads to increased protein content in human muscle cells
- Stéphanie Chanon
- , Blandine Chazarin
- & Etienne Lefai
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| Open AccessSubcellular localisation modulates ubiquitylation and degradation of Ascl1
- Sébastien Gillotin
- , John D. Davies
- & Anna Philpott
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| Open AccessOptimization of ClpXP activity and protein synthesis in an E. coli extract-based cell-free expression system
- Xinying Shi
- , Ti Wu
- & Simpson Joseph
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| Open AccessNovel ubiquitin-independent nucleolar c-Myc degradation pathway mediated by antizyme 2
- Noriyuki Murai
- , Yasuko Murakami
- & Senya Matsufuji
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| Open AccessHigh throughput protease profiling comprehensively defines active site specificity for thrombin and ADAMTS13
- Colin A. Kretz
- , Kärt Tomberg
- & David Ginsburg
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| Open AccessTemporal downregulation of the polyubiquitin gene Ubb affects neuronal differentiation, but not maturation, in cells cultured in vitro
- Byung-Kwon Jung
- , Chul-Woo Park
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| Open AccessMouse Antibody of IgM Class is Prone to Non-Enzymatic Cleavage between CH1 and CH2 Domains
- Tomasz Klaus
- , Krystyna Stalińska
- & Joanna Bereta
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| Open AccessMilder degenerative effects of Carfilzomib vs. Bortezomib in the Drosophila model: a link to clinical adverse events
- Eleni N. Tsakiri
- , Evangelos Terpos
- & Ioannis P. Trougakos
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| Open AccessThe serine proteinase hepsin is an activator of pro-matrix metalloproteinases: molecular mechanisms and implications for extracellular matrix turnover
- David J. Wilkinson
- , Antoine Desilets
- & Andrew D. Rowan
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| Open Accessp300-mediated acetylation increased the protein stability of HIPK2 and enhanced its tumor suppressor function
- Jong-Ryoul Choi
- , Seo-Young Lee
- & Shin Jung Kang
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| Open AccessProteolytic cleavage of transmembrane cell adhesion molecule L1 by extracellular matrix molecule Reelin is important for mouse brain development
- David Lutz
- , Ahmed Sharaf
- & Melitta Schachner
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| Open AccessThe Kunitz Domain I of Hepatocyte Growth Factor Activator Inhibitor-2 Inhibits Matriptase Activity and Invasive Ability of Human Prostate Cancer Cells
- Shang-Ru Wu
- , Chen-Hsin Teng
- & Ming-Shyue Lee
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| Open AccessThe lipid raft-dwelling protein US9 can be manipulated to target APP compartmentalization, APP processing, and neurodegenerative disease pathogenesis
- Renato Brandimarti
- , Gordon S. Hill
- & Olimpia Meucci
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| Open AccessElimination of a signal sequence-uncleaved form of defective HLA protein through BAG6
- Koki Yamamoto
- , Mizuki Hayashishita
- & Hiroyuki Kawahara
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| Open AccessMultiple regulatory mechanisms of the biological function of NRF3 (NFE2L3) control cancer cell proliferation
- A. M. Masudul Azad Chowdhury
- , Hiroki Katoh
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| Open Access6-bromo-indirubin-3′-oxime (6BIO), a Glycogen synthase kinase-3β inhibitor, activates cytoprotective cellular modules and suppresses cellular senescence-mediated biomolecular damage in human fibroblasts
- Aimilia D. Sklirou
- , Nicolas Gaboriaud-Kolar
- & Ioannis P. Trougakos
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| Open AccessA novel function of cIAP1 as a mediator of CHIP-driven eIF4E regulation
- Tae Woong Seo
- , Ji Sun Lee
- & Soon Ji Yoo
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| Open AccessThe role of the immunoproteasome in interferon-γ-mediated microglial activation
- Kasey E. Moritz
- , Nikki M. McCormack
- & Barrington G. Burnett
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| Open AccessMultiple E3s promote the degradation of histone H3 variant Cse4
- Haili Cheng
- , Xin Bao
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| Open AccessDrosophila protease ClpXP specifically degrades DmLRPPRC1 controlling mitochondrial mRNA and translation
- Yuichi Matsushima
- , Yuta Hirofuji
- & Dongchon Kang
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| Open AccessMass spectrometry-based determination of Kallikrein-related peptidase 7 (KLK7) cleavage preferences and subsite dependency
- Lakmali Munasinghage Silva
- , Thomas Stoll
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| Open AccessComprehensive analysis of human protein N-termini enables assessment of various protein forms
- Jeonghun Yeom
- , Shinyeong Ju
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| Open AccessStability of the PHF10 subunit of PBAF signature module is regulated by phosphorylation: role of β-TrCP
- Victor V. Tatarskiy
- , Yuriy P. Simonov
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| Open AccessDeviation of the typical AAA substrate-threading pore prevents fatal protein degradation in yeast Cdc48
- Masatoshi Esaki
- , Md. Tanvir Islam
- & Teru Ogura
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| Open AccessRecurrent background mutations in WHI2 impair proteostasis and degradation of misfolded cytosolic proteins in Saccharomyces cerevisiae
- Sophie A. Comyn
- , Stéphane Flibotte
- & Thibault Mayor
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| Open AccessDynamics and ligand-induced conformational changes in human prolyl oligopeptidase analyzed by hydrogen/deuterium exchange mass spectrometry
- Alexandra Tsirigotaki
- , Roos Van Elzen
- & Anastassios Economou
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| Open AccessDifferent Polyubiquitinated Bodies in Human Dendritic Cells: IL-4 Causes PaCS During Differentiation while LPS or IFNα Induces DALIS During Maturation
- Daniela Montagna
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- & Enrico Solcia
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| Open AccessMKRN2 is a novel ubiquitin E3 ligase for the p65 subunit of NF-κB and negatively regulates inflammatory responses
- Chanyoung Shin
- , Yuma Ito
- & Takashi Tanaka
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| Open Access20S immunoproteasomes remove formaldehyde-damaged cytoplasmic proteins suppressing caspase-independent cell death
- Sara Ortega-Atienza
- , Casey Krawic
- & Anatoly Zhitkovich
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| Open AccessThe role of Lon-mediated proteolysis in the dynamics of mitochondrial nucleic acid-protein complexes
- Nina Kunová
- , Gabriela Ondrovičová
- & Vladimír Pevala
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| Open AccessApigenin-induced lysosomal degradation of β-catenin in Wnt/β-catenin signaling
- Chung-Ming Lin
- , Hsin-Han Chen
- & Hui-Jye Chen
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| Open AccessTandem UIMs confer Lys48 ubiquitin chain substrate preference to deubiquitinase USP25
- Kohei Kawaguchi
- , Kazune Uo
- & Masayuki Komada
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| Open AccessIdentification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation
- Emilie Andrio
- , Romain Lotte
- & Emmanuel Lemichez
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| Open AccessBoth Drosophila matrix metalloproteinases have released and membrane-tethered forms but have different substrates
- Kimberly S. LaFever
- , Xiaoxi Wang
- & Andrea Page-McCaw
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| Open AccessAlternative exon skipping biases substrate preference of the deubiquitylase USP15 for mysterin/RNF213, the moyamoya disease susceptibility factor
- Yuri Kotani
- , Daisuke Morito
- & Kazuhiro Nagata
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| Open AccessDentin Sialoprotein is a Novel Substrate of Matrix Metalloproteinase 9 in vitro and in vivo
- Guohua Yuan
- , Lei Chen
- & Shuo Chen
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| Open AccessAndrogen Mediated Regulation of Endoplasmic Reticulum-Associated Degradation and its Effects on Prostate Cancer
- Yalcin Erzurumlu
- & Petek Ballar
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| Open AccessUbiquitin Ligase NEDD4 Regulates PPARγ Stability and Adipocyte Differentiation in 3T3-L1 Cells
- Jing Jing Li
- , Ruishan Wang
- & Francesca-Fang Liao
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| Open AccessGrowth factor and co-receptor release by structural regulation of substrate metalloprotease accessibility
- Liseth M. Parra
- , Monika Hartmann
- & Andreas Herrlich