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Angiotensin II type 1a receptor deficiency alleviates muscle atrophy after denervation
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Disruption of male fertility-critical Dcaf17 dysregulates mouse testis transcriptome
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Efficient terminal erythroid differentiation requires the APC/C cofactor Cdh1 to limit replicative stress in erythroblasts
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Reciprocal interaction between SIRT6 and APC/C regulates genomic stability
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The ubiquitin ligase Cullin-1 associates with chromatin and regulates transcription of specific c-MYC target genes
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Cryptochromes modulate E2F family transcription factors
- Alanna B. Chan
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Inflammatory bowel disease-associated ubiquitin ligase RNF183 promotes lysosomal degradation of DR5 and TRAIL-induced caspase activation
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WDR76 mediates obesity and hepatic steatosis via HRas destabilization
- Jong-Chan Park
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Stress-induced phospho-ubiquitin formation causes parkin degradation
- Lyudmila Kovalchuke
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Atrogin-1/MAFbx mRNA expression is regulated by histone deacetylase 1 in rat soleus muscle under hindlimb unloading
- Ekaterina P. Mochalova
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Neuralized family member NEURL1 is a ubiquitin ligase for the cGMP-specific phosphodiesterase 9A
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Regulation of liver receptor homologue-1 by DDB2 E3 ligase activity is critical for hepatic glucose metabolism
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The conserved RNA recognition motif and C3H1 domain of the Not4 ubiquitin ligase regulate in vivo ligase function
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A novel function of cIAP1 as a mediator of CHIP-driven eIF4E regulation
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Multiple E3s promote the degradation of histone H3 variant Cse4
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Stability of the PHF10 subunit of PBAF signature module is regulated by phosphorylation: role of β-TrCP
- Victor V. Tatarskiy
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Recurrent background mutations in WHI2 impair proteostasis and degradation of misfolded cytosolic proteins in Saccharomyces cerevisiae
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MKRN2 is a novel ubiquitin E3 ligase for the p65 subunit of NF-κB and negatively regulates inflammatory responses
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Androgen Mediated Regulation of Endoplasmic Reticulum-Associated Degradation and its Effects on Prostate Cancer
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Ubiquitin Ligase NEDD4 Regulates PPARγ Stability and Adipocyte Differentiation in 3T3-L1 Cells
- Jing Jing Li
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Indoxyl sulfate potentiates skeletal muscle atrophy by inducing the oxidative stress-mediated expression of myostatin and atrogin-1
- Yuki Enoki
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Genome-wide identification and gene expression profiling of ubiquitin ligases for endoplasmic reticulum protein degradation
- Masayuki Kaneko
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A C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125
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β-TrCP-mediated ubiquitination and degradation of liver-enriched transcription factor CREB-H
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MASTL(Greatwall) regulates DNA damage responses by coordinating mitotic entry after checkpoint recovery and APC/C activation
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Substrates of the ASB2α E3 ubiquitin ligase in dendritic cells
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Expression profile of a Caenorhabditis elegans model of adult neuronal ceroid lipofuscinosis reveals down regulation of ubiquitin E3 ligase components
- Hannah V. McCue
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Nanobody-targeted E3-ubiquitin ligase complex degrades nuclear proteins
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The Cullin 4A/B-DDB1-Cereblon E3 Ubiquitin Ligase Complex Mediates the Degradation of CLC-1 Chloride Channels
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K63 linked ubiquitin chain formation is a signal for HIF1A degradation by Chaperone-Mediated Autophagy
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Inhibition of post-translational N-glycosylation by HRD1 that controls the fate of ABCG5/8 transporter
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PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
- Kahori Shiba-Fukushima
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Primate-specific isoform of Nedd4-1 regulates substrate binding via Ser/Thr phosphorylation and 14-3-3 binding