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Glucose restriction in Saccharomyces cerevisiae modulates the phosphorylation pattern of the 20S proteasome and increases its activity
- Renata Naporano Bicev
- , Maximilia Frazão de Souza Degenhardt
- & Fernanda Marques da Cunha
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| Open Access
The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels
- Monika Krošel
- , Marcel Gabathuler
- & Kerstin Klein
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| Open Access
Evaluation of the NRF1-proteasome axis as a therapeutic target in breast cancer
- Holly A. Byers
- , Amy N. Brooks
- & Senthil K. Radhakrishnan
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| Open Access
NEIL3-mediated proteasomal degradation facilitates the repair of cisplatin-induced DNA damage in human cells
- Umit Aliyaskarova
- , Yeldar Baiken
- & Regina Groisman
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| Open Access
FMRP, FXR1 protein and Dlg4 mRNA, which are associated with fragile X syndrome, are involved in the ubiquitin–proteasome system
- Hideo Shimizu
- & Hirohiko Hohjoh
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Prolonged treatment with the proteasome inhibitor MG-132 induces apoptosis in PC12 rat pheochromocytoma cells
- Oktávia Tarjányi
- , Julian Haerer
- & György Sétáló Jr.
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A new ultradian rhythm in mammalian cell dry mass observed by holography
- Lamya Ghenim
- , Cédric Allier
- & Xavier Gidrol
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Functional impacts of the ubiquitin–proteasome system on DNA damage recognition in global genome nucleotide excision repair
- Wataru Sakai
- , Mayumi Yuasa-Sunagawa
- & Kaoru Sugasawa
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Tagging the proteasome active site β5 causes tag specific phenotypes in yeast
- Kenrick A. Waite
- , Alicia Burris
- & Jeroen Roelofs
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Efficiency of the four proteasome subtypes to degrade ubiquitinated or oxidized proteins
- Joanna Abi Habib
- , Etienne De Plaen
- & Benoit J. Van den Eynde
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Article
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Two-Step Mechanism of Cyclin B Degradation Initiated by Proteolytic Cleavage with the 26 S Proteasome in Fish
- Toshinobu Tokumoto
- , Md. Forhad Hossain
- & Mika Tokumoto
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| Open Access
MG132 exerts anti-viral activity against HSV-1 by overcoming virus-mediated suppression of the ERK signaling pathway
- Hanako Ishimaru
- , Kohei Hosokawa
- & Masahiro Fujimuro
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Cell cycle–dependent localization of the proteasome to chromatin
- Yuki Kito
- , Masaki Matsumoto
- & Keiichi I. Nakayama
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| Open Access
Disordered region of cereblon is required for efficient degradation by proteolysis-targeting chimera
- Kidae Kim
- , Dong Ho Lee
- & Jeong-Hoon Kim
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| Open Access
Ubiquitin receptors are required for substrate-mediated activation of the proteasome’s unfolding ability
- Mary D. Cundiff
- , Christina M. Hurley
- & Daniel A. Kraut
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Proteasome dysfunction in alveolar type 2 epithelial cells is associated with acute respiratory distress syndrome
- Sneha Sitaraman
- , Cheng-Lun Na
- & Timothy E. Weaver
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| Open Access
Proteasome subunit α1 overexpression preferentially drives canonical proteasome biogenesis and enhances stress tolerance in yeast
- Lauren A. Howell
- , Anna K. Peterson
- & Robert J. Tomko Jr.
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| Open Access
A repetitive acidic region contributes to the extremely rapid degradation of the cell-context essential protein TRIM52
- Kathrin Hacker
- , Stefan Benke
- & Gijs A. Versteeg
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| Open Access
Proteasome β5 subunit overexpression improves proteostasis during aging and extends lifespan in Drosophila melanogaster
- Nga N. Nguyen
- , Anil Rana
- & Jae H. Hur
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Efficient production of a mature and functional gamma secretase protease
- Imran Khan
- , Sudarsan Krishnaswamy
- & Giuseppe Verdile
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Defective immuno- and thymoproteasome assembly causes severe immunodeficiency
- Irina Treise
- , Eva M. Huber
- & Dirk H. Busch
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Novel ubiquitin-independent nucleolar c-Myc degradation pathway mediated by antizyme 2
- Noriyuki Murai
- , Yasuko Murakami
- & Senya Matsufuji
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Milder degenerative effects of Carfilzomib vs. Bortezomib in the Drosophila model: a link to clinical adverse events
- Eleni N. Tsakiri
- , Evangelos Terpos
- & Ioannis P. Trougakos
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| Open Access
p300-mediated acetylation increased the protein stability of HIPK2 and enhanced its tumor suppressor function
- Jong-Ryoul Choi
- , Seo-Young Lee
- & Shin Jung Kang
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| Open Access
Elimination of a signal sequence-uncleaved form of defective HLA protein through BAG6
- Koki Yamamoto
- , Mizuki Hayashishita
- & Hiroyuki Kawahara
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| Open Access
6-bromo-indirubin-3′-oxime (6BIO), a Glycogen synthase kinase-3β inhibitor, activates cytoprotective cellular modules and suppresses cellular senescence-mediated biomolecular damage in human fibroblasts
- Aimilia D. Sklirou
- , Nicolas Gaboriaud-Kolar
- & Ioannis P. Trougakos
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| Open Access
The role of the immunoproteasome in interferon-γ-mediated microglial activation
- Kasey E. Moritz
- , Nikki M. McCormack
- & Barrington G. Burnett
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| Open Access
Deviation of the typical AAA substrate-threading pore prevents fatal protein degradation in yeast Cdc48
- Masatoshi Esaki
- , Md. Tanvir Islam
- & Teru Ogura
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Different Polyubiquitinated Bodies in Human Dendritic Cells: IL-4 Causes PaCS During Differentiation while LPS or IFNα Induces DALIS During Maturation
- Daniela Montagna
- , Patrizia Sommi
- & Enrico Solcia
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| Open Access
Expression of immunoproteasome genes is regulated by cell-intrinsic and –extrinsic factors in human cancers
- Alexandre Rouette
- , Assya Trofimov
- & Claude Perreault
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| Open Access
The polyglutamine-expanded androgen receptor responsible for spinal and bulbar muscular atrophy inhibits the APC/CCdh1 ubiquitin ligase complex
- Laura C. Bott
- , Florian A. Salomons
- & Nico P. Dantuma
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| Open Access
Phosphorylation of the C-terminal tail of proteasome subunit α7 is required for binding of the proteasome quality control factor Ecm29
- Prashant S. Wani
- , Anjana Suppahia
- & Jeroen Roelofs
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| Open Access
Exposure to Melan-A/MART-126-35 tumor epitope specific CD8+T cells reveals immune escape by affecting the ubiquitin-proteasome system (UPS)
- Frédéric Ebstein
- , Martin Keller
- & Ulrike Seifert
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| Open Access
ahg12 is a dominant proteasome mutant that affects multiple regulatory systems for germination of Arabidopsis
- Shimpei Hayashi
- & Takashi Hirayama
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| Open Access
Proteasome activators, PA28γ and PA200, play indispensable roles in male fertility
- Lin Huang
- , Kousuke Haratake
- & Tomoki Chiba
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| Open Access
A bead-based cleavage method for large-scale identification of protease substrates
- Chunli Wang
- , Mingliang Ye
- & Hanfa Zou
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| Open Access
Perilipin2 plays a positive role in adipocytes during lipolysis by escaping proteasomal degradation
- Yu Takahashi
- , Akihiro Shinoda
- & Ryuichiro Sato
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| Open Access
Induction of cell death by the novel proteasome inhibitor marizomib in glioblastoma in vitro and in vivo
- Christa A. Manton
- , Blake Johnson
- & Joya Chandra
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| Open Access
Characterization of Rv0888, a Novel Extracellular Nuclease from Mycobacterium tuberculosis
- Guanghui Dang
- , Jun Cao
- & Siguo Liu
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| Open Access
Proteasome Activation is Mediated via a Functional Switch of the Rpt6 C-terminal Tail Following Chaperone-dependent Assembly
- Vladyslava Sokolova
- , Frances Li
- & Soyeon Park
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Alpha-ring Independent Assembly of the 20S Proteasome
- Dilrajkaur Panfair
- , Aishwarya Ramamurthy
- & Andrew R. Kusmierczyk
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iRhom1 regulates proteasome activity via PAC1/2 under ER stress
- WonJae Lee
- , YoungDoo Kim
- & Yong-Keun Jung
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Ubiquitin-specific protease 14 modulates degradation of cellular prion protein
- Takujiro Homma
- , Daisuke Ishibashi
- & Noriyuki Nishida
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| Open Access
Facilitated Tau Degradation by USP14 Aptamers via Enhanced Proteasome Activity
- Jung Hoon Lee
- , Seung Kyun Shin
- & Min Jae Lee
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| Open Access
Acute ER stress regulates amyloid precursor protein processing through ubiquitin-dependent degradation
- Eun Sun Jung
- , HyunSeok Hong
- & Inhee Mook-Jung
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| Open Access
Cdc48-independent proteasomal degradation coincides with a reduced need for ubiquitylation
- Daniela Gödderz
- , Christian Heinen
- & Nico P. Dantuma
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Article
| Open Access
Removal of damaged proteins during ES cell fate specification requires the proteasome activator PA28
- Malin Hernebring
- , Åsa Fredriksson
- & Thomas Nyström
Yeast 26S proteasome nuclear import is coupled to nucleus-specific degradation of the karyopherin adaptor protein Sts1