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| Open AccessOTUD4 enhances TGFβ signalling through regulation of the TGFβ receptor complex
- Patrick William Jaynes
- , Prasanna Vasudevan Iyengar
- & Pieter Johan Adam Eichhorn
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| Open AccessPredominant synthesis of giant myofibrillar proteins in striated muscles of the long-tailed ground squirrel Urocitellus undulatus during interbout arousal
- Svetlana Popova
- , Anna Ulanova
- & Ivan Vikhlyantsev
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| Open AccessSubstitution of Thr572 to Ala in mouse c-Myb attenuates progression of early erythroid differentiation
- Kyoko Kitagawa
- , Chiharu Uchida
- & Masatoshi Kitagawa
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| Open AccessThe ubiquitin ligase Cullin-1 associates with chromatin and regulates transcription of specific c-MYC target genes
- Melanie A. Sweeney
- , Polina Iakova
- & Andre Catic
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| Open AccessFormaldehyde treatment of proteins enhances proteolytic degradation by the endo-lysosomal protease cathepsin S
- Thomas J. M. Michiels
- , Hugo D. Meiring
- & Bernard Metz
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| Open AccessRole of the activation peptide in the mechanism of protein C activation
- Bosko M. Stojanovski
- , Leslie A. Pelc
- & Enrico Di Cera
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| Open AccessGlobal analysis of protein degradation in prion infected cells
- Charles R. Hutti
- , Kevin A. Welle
- & Sina Ghaemmaghami
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| Open AccessTwo-Step Mechanism of Cyclin B Degradation Initiated by Proteolytic Cleavage with the 26 S Proteasome in Fish
- Toshinobu Tokumoto
- , Md. Forhad Hossain
- & Mika Tokumoto
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| Open AccessThe aryl hydrocarbon receptor pathway controls matrix metalloproteinase-1 and collagen levels in human orbital fibroblasts
- Elisa Roztocil
- , Christine L. Hammond
- & Collynn F. Woeller
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| Open AccessGiant magnetoresistive biosensors for real-time quantitative detection of protease activity
- Sandeep Adem
- , Sonal Jain
- & Drew A. Hall
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| Open AccessMG132 exerts anti-viral activity against HSV-1 by overcoming virus-mediated suppression of the ERK signaling pathway
- Hanako Ishimaru
- , Kohei Hosokawa
- & Masahiro Fujimuro
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| Open AccessCell surface processing of the P1 adhesin of Mycoplasma pneumoniae identifies novel domains that bind host molecules
- Michael Widjaja
- , Iain James Berry
- & Steven Philip Djordjevic
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| Open AccessCell cycle–dependent localization of the proteasome to chromatin
- Yuki Kito
- , Masaki Matsumoto
- & Keiichi I. Nakayama
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| Open AccessCryptochromes modulate E2F family transcription factors
- Alanna B. Chan
- , Anne-Laure Huber
- & Katja A. Lamia
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| Open AccessCharacterization of cereblon-dependent targeted protein degrader by visualizing the spatiotemporal ternary complex formation in cells
- Tomohiro Kaji
- , Hiroshi Koga
- & Kenji Hayata
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| Open AccessSIAH2-mediated and organ-specific restriction of HO-1 expression by a dual mechanism
- Shashipavan Chillappagari
- , Ratnal Belapurkar
- & M. Lienhard Schmitz
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| Open AccessTAK-242, a specific inhibitor of Toll-like receptor 4 signalling, prevents endotoxemia-induced skeletal muscle wasting in mice
- Yuko Ono
- , Yuko Maejima
- & Joji Kotani
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| Open AccessCathepsin B overexpression induces degradation of perilipin 1 to cause lipid metabolism dysfunction in adipocytes
- Yuhei Mizunoe
- , Masaki Kobayashi
- & Yoshikazu Higami
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| Open AccessTargeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation
- Sylwia Jones
- , Peter J. King
- & Daniel Hochhauser
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| Open AccessInflammatory bowel disease-associated ubiquitin ligase RNF183 promotes lysosomal degradation of DR5 and TRAIL-induced caspase activation
- Yan Wu
- , Yuka Kimura
- & Masayuki Kaneko
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| Open AccessWDR76 mediates obesity and hepatic steatosis via HRas destabilization
- Jong-Chan Park
- , Woo-Jeong Jeong
- & Kang-Yell Choi
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| Open AccessDisordered region of cereblon is required for efficient degradation by proteolysis-targeting chimera
- Kidae Kim
- , Dong Ho Lee
- & Jeong-Hoon Kim
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| Open AccessSelective autophagy, lipophagy and mitophagy, in the Harderian gland along the oestrous cycle: a potential retrieval effect of melatonin
- Marina García-Macia
- , Adrián Santos-Ledo
- & Ana Coto-Montes
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| Open AccessUbiquitin receptors are required for substrate-mediated activation of the proteasome’s unfolding ability
- Mary D. Cundiff
- , Christina M. Hurley
- & Daniel A. Kraut
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| Open AccessADAM10 is Expressed by Ameloblasts, Cleaves the RELT TNF Receptor Extracellular Domain and Facilitates Enamel Development
- Atsushi Ikeda
- , Shifa Shahid
- & John D. Bartlett
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| Open AccessProteasome dysfunction in alveolar type 2 epithelial cells is associated with acute respiratory distress syndrome
- Sneha Sitaraman
- , Cheng-Lun Na
- & Timothy E. Weaver
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| Open AccessProteasome subunit α1 overexpression preferentially drives canonical proteasome biogenesis and enhances stress tolerance in yeast
- Lauren A. Howell
- , Anna K. Peterson
- & Robert J. Tomko Jr.
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| Open AccessStress-induced phospho-ubiquitin formation causes parkin degradation
- Lyudmila Kovalchuke
- , Eugene V. Mosharov
- & Lloyd A. Greene
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| Open AccessAtrogin-1/MAFbx mRNA expression is regulated by histone deacetylase 1 in rat soleus muscle under hindlimb unloading
- Ekaterina P. Mochalova
- , Svetlana P. Belova
- & Tatiana L. Nemirovskaya
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| Open AccessCytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system
- Karthik Selvaraju
- , Arjan Mofers
- & Stig Linder
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| Open AccessTargeting DNAJB9, a novel ER luminal co-chaperone, to rescue ΔF508-CFTR
- Yunjie Huang
- , Kavisha Arora
- & Anjaparavanda P. Naren
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| Open AccessElastolytic activity of cysteine cathepsins K, S, and V promotes vascular calcification
- Pierre-Marie Andrault
- , Preety Panwar
- & Dieter Brömme
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| Open AccessA repetitive acidic region contributes to the extremely rapid degradation of the cell-context essential protein TRIM52
- Kathrin Hacker
- , Stefan Benke
- & Gijs A. Versteeg
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| Open AccessStructure and tailspike glycosidase machinery of ORF212 from E. coli O157:H7 phage CBA120 (TSP3)
- Julia Greenfield
- , Xiaoran Shang
- & Osnat Herzberg
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| Open AccessNeuralized family member NEURL1 is a ubiquitin ligase for the cGMP-specific phosphodiesterase 9A
- Kati Taal
- , Jürgen Tuvikene
- & Tõnis Timmusk
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| Open AccessStructural basis of βTrCP1-associated GLI3 processing
- Shagufta Shafique
- & Sajid Rashid
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| Open AccessProbing prothrombin structure by limited proteolysis
- Laura Acquasaliente
- , Leslie A. Pelc
- & Enrico Di Cera
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| Open AccessRegulation of liver receptor homologue-1 by DDB2 E3 ligase activity is critical for hepatic glucose metabolism
- Tsai-Chun Lai
- & Meng-Chun Hu
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| Open AccessGlycosaminoglycans influence enzyme activity of MMP2 and MMP2/TIMP3 complex formation - Insights at cellular and molecular level
- Gloria Ruiz-Gómez
- , Sarah Vogel
- & Ute Hempel
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| Open AccessL1cam-mediated developmental processes of the nervous system are differentially regulated by proteolytic processing
- Cecilie Linneberg
- , Christian Liebst Frisk Toft
- & Lisbeth S. Laursen
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| Open AccessProteasome β5 subunit overexpression improves proteostasis during aging and extends lifespan in Drosophila melanogaster
- Nga N. Nguyen
- , Anil Rana
- & Jae H. Hur
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| Open AccessGPDPLQ1237—A Type II Collagen Neo-Epitope Biomarker of Osteoclast- and Inflammation-Derived Cartilage Degradation in vitro
- Henrik Löfvall
- , Anna Katri
- & Kim Henriksen
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| Open AccessVangl2 interaction plays a role in the proteasomal degradation of Prickle2
- Tadahiro Nagaoka
- , Mikio Furuse
- & Masashi Kishi
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| Open AccessMammalian plasma fetuin-B is a selective inhibitor of ovastacin and meprin metalloproteinases
- Konstantin Karmilin
- , Carlo Schmitz
- & Walter Stöcker
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| Open AccessRapid degradation of progressive ankylosis protein (ANKH) in craniometaphyseal dysplasia
- Jitendra Kanaujiya
- , Edward Bastow
- & I-Ping Chen
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Article
| Open AccessGenetic interactions between ABA signalling and the Arg/N-end rule pathway during Arabidopsis seedling establishment
- Hongtao Zhang
- , Lucy Gannon
- & Frederica L. Theodoulou
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| Open AccessThe E3 ubiquitin ligase Trim13 regulates Nur77 stability via casein kinase 2α
- Bin Huang
- , Han Zhong Pei
- & Suk-Hwan Baek
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| Open AccessPerrault syndrome type 3 caused by diverse molecular defects in CLPP
- Erica J. Brodie
- , Hanmiao Zhan
- & David A. Dougan
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| Open AccessEfficient production of a mature and functional gamma secretase protease
- Imran Khan
- , Sudarsan Krishnaswamy
- & Giuseppe Verdile