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| Open AccessThe hypoxia sensitive metal transcription factor MTF-1 activates NCX1 brain promoter and participates in remote postconditioning neuroprotection in stroke
- Valeria Valsecchi
- , Giusy Laudati
- & Giuseppe Pignataro
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Article
| Open AccessDevelopment of a bispecific immune engager using a recombinant malaria protein
- Mie A. Nordmaj
- , Morgan E. Roberts
- & Ali Salanti
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Article
| Open AccessUtidelone inhibits growth of colorectal cancer cells through ROS/JNK signaling pathway
- Fuli Li
- , Tinglei Huang
- & Shuiping Tu
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| Open AccessOleandrin, a cardiac glycoside, induces immunogenic cell death via the PERK/elF2α/ATF4/CHOP pathway in breast cancer
- Xiaoxi Li
- , Jian Zheng
- & Shu-lan Sun
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Article
| Open AccessPhosphatase PP2A enhances MCL-1 protein half-life in multiple myeloma cells
- Anne Slomp
- , Laura M. Moesbergen
- & Victor Peperzak
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| Open AccessMutant p53 promotes RCP-dependent chemoresistance coinciding with increased delivery of P-glycoprotein to the plasma membrane
- Vinaya Phatak
- , Yannick von Grabowiecki
- & Patricia A. J. Muller
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Article
| Open AccessMolecular subtype-specific responses of colon cancer cells to the SMAC mimetic Birinapant
- Michael Fichtner
- , Emir Bozkurt
- & Jochen H. M. Prehn
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| Open AccessProteoglycan-4 is correlated with longer survival in HCC patients and enhances sorafenib and regorafenib effectiveness via CD44 in vitro
- Francesco Dituri
- , Rosanna Scialpi
- & Gianluigi Giannelli
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Article
| Open AccessImmunomodulatory activity of IR700-labelled affibody targeting HER2
- Justyna Mączyńska
- , Chiara Da Pieve
- & Gabriela Kramer-Marek
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Article
| Open AccessDifferential sensitivity of acute myeloid leukemia cells to daunorubicin depends on P2X7A versus P2X7B receptor expression
- Anna Pegoraro
- , Elisa Orioli
- & Elena Adinolfi
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Article
| Open AccessHOTAIR contributes to the carcinogenesis of gastric cancer via modulating cellular and exosomal miRNAs level
- Jie Zhang
- , Wei-qing Qiu
- & Zhi-yong Shen
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Article
| Open AccessNEDDylation negatively regulates ERRβ expression to promote breast cancer tumorigenesis and progression
- Sanoj K. Naik
- , Eric W.-F. Lam
- & Sandip K. Mishra
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Article
| Open AccessCombined treatment with CBP and BET inhibitors reverses inadvertent activation of detrimental super enhancer programs in DIPG cells
- Maria Wiese
- , Feda H. Hamdan
- & Christof M. Kramm
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| Open AccessTRPA1 mediates damage of the retina induced by ischemia and reperfusion in mice
- Daniel Souza Monteiro de Araújo
- , Francesco De Logu
- & Karin da Costa Calaza
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| Open AccessBCG vaccination policy and preventive chloroquine usage: do they have an impact on COVID-19 pandemic?
- Abhibhav Sharma
- , Saurabh Kumar Sharma
- & Gobardhan Das
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| Open AccessActivation of adenosine A3 receptor protects retinal ganglion cells from degeneration induced by ocular hypertension
- Raquel Boia
- , Manuel Salinas-Navarro
- & Ana Raquel Santiago
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| Open AccessLoss of Spry1 reduces growth of BRAFV600-mutant cutaneous melanoma and improves response to targeted therapy
- Barbara Montico
- , Francesca Colizzi
- & Elisabetta Fratta
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Article
| Open AccessTargeting Src family kinase member Fyn by Saracatinib attenuated liver fibrosis in vitro and in vivo
- Guifang Du
- , Jing Wang
- & Yinying Lu
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Article
| Open AccessMetformin reduces HGF-induced resistance to alectinib via the inhibition of Gab1
- Hengyi Chen
- , Caiyu Lin
- & Yong He
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Article
| Open AccessEffects of thrombospondin-4 on pro-inflammatory phenotype differentiation and apoptosis in macrophages
- Mohammed Tanjimur Rahman
- , Santoshi Muppala
- & Olga Stenina-Adognravi
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Article
| Open AccessCircular RNA circ_001621 promotes osteosarcoma cells proliferation and migration by sponging miR-578 and regulating VEGF expression
- Xianglu Ji
- , Liping Shan
- & Ming He
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| Open AccessIdentification of a transient state during the acquisition of temozolomide resistance in glioblastoma
- Marion Rabé
- , Solenne Dumont
- & François M. Vallette
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Article
| Open AccessNovel HDAC inhibitor Chidamide synergizes with Rituximab to inhibit diffuse large B-cell lymphoma tumour growth by upregulating CD20
- Xu-Wen Guan
- , Hua-Qing Wang
- & Feng-Ting Liu
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| Open AccessGSK3β is a key regulator of the ROS-dependent necrotic death induced by the quinone DMNQ
- Sonia Ciotti
- , Luca Iuliano
- & Claudio Brancolini
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| Open AccessBID and the α-bisabolol-triggered cell death program: converging on mitochondria and lysosomes
- Antonella Rigo
- , Isacco Ferrarini
- & Fabrizio Vinante
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| Open AccessBET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells
- Matko Čančer
- , Lisa F. Drews
- & Fredrik J. Swartling
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| Open AccessFTY720 induces non-canonical phosphatidylserine externalization and cell death in acute myeloid leukemia
- Megan M. Young
- , Van Bui
- & Hong-Gang Wang
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| Open AccessDirect impact of cisplatin on mitochondria induces ROS production that dictates cell fate of ovarian cancer cells
- Markus Kleih
- , Kathrin Böpple
- & Frank Essmann
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Article
| Open AccessImpaired Wnt/β-catenin pathway leads to dysfunction of intestinal regeneration during necrotizing enterocolitis
- Bo Li
- , Carol Lee
- & Agostino Pierro
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| Open AccessC/EBPα deficiency in podocytes aggravates podocyte senescence and kidney injury in aging mice
- Liwen Zhang
- , Fangfang Zhou
- & Nan Chen
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| Open AccessExosome-mediated uptake of mast cell tryptase into the nucleus of melanoma cells: a novel axis for regulating tumor cell proliferation and gene expression
- Fabio Rabelo Melo
- , Sebastin Santosh Martin
- & Gunnar Pejler
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| Open AccessBlockade of HMGB1 signaling pathway by ethyl pyruvate inhibits tumor growth in diffuse large B-cell lymphoma
- Tian Zhang
- , Xu-Wen Guan
- & Li Jia
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| Open AccessLoss of the androgen receptor suppresses intrarenal calcium oxalate crystals deposition via altering macrophage recruitment/M2 polarization with change of the miR-185-5p/CSF-1 signals
- Wei Zhu
- , Zhijian Zhao
- & Chawnshang Chang
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Article
| Open AccessTargeting autophagy potentiates antitumor activity of Met-TKIs against Met-amplified gastric cancer
- Xiaoting Lin
- , Zhi Peng
- & Lin Shen
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Original Article
| Open AccessPreclinical anti-arthritic study and pharmacokinetic properties of a potent histone deacetylase inhibitor MPT0G009
- I-N Hsieh
- , J-P Liou
- & C-R Yang
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Original Article
| Open AccessThe organotelluride catalyst LAB027 prevents colon cancer growth in the mice
- R Coriat
- , W Marut
- & F Batteux