Molecular engineering

Definition

Molecular engineering includes methods for the design and synthesis of novel molecules with desirable physical properties or functionalities.

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Latest Research and Reviews

  • Reviews |

    Many bacteria can infect and persist inside their hosts for long periods of time. In this Review, Fisher, Gollan and Helaine discuss recent developments in our understanding of bacterial persisters and their potential implications for the treatment of persistent infections.

    • Robert A. Fisher
    • , Bridget Gollan
    •  & Sophie Helaine
  • Research |

    The design and mutagenesis of an α-helix-containing monomeric miniprotein, PPα-Tyr, provide insights into weak noncovalent CH–π interactions that help define and stabilize folded proteins and protein–ligand interactions.

    • Emily G Baker
    • , Christopher Williams
    • , Kieran L Hudson
    • , Gail J Bartlett
    • , Jack W Heal
    • , Kathryn L Porter Goff
    • , Richard B Sessions
    • , Matthew P Crump
    •  & Derek N Woolfson
  • Research |

    A synthetic biology system composed of light-wavelength-responsive genetic regulators, signal-processing circuits and pigment-production pathways have resulted in an Escherichia coli strain that can record color images in RGB format.

    • Jesus Fernandez-Rodriguez
    • , Felix Moser
    • , Miryoung Song
    •  & Christopher A Voigt
  • Research | | open

    The properties of many transmembrane or aggregation-prone proteins make them difficult to recombinantly express. Here the authors use a modified N-terminal domain of a spider silk protein to express and purify several difficult to express proteins at levels considerably higher than with conventional tags.

    • Nina Kronqvist
    • , Médoune Sarr
    • , Anton Lindqvist
    • , Kerstin Nordling
    • , Martins Otikovs
    • , Luca Venturi
    • , Barbara Pioselli
    • , Pasi Purhonen
    • , Michael Landreh
    • , Henrik Biverstål
    • , Zigmantas Toleikis
    • , Lisa Sjöberg
    • , Carol V. Robinson
    • , Nicola Pelizzi
    • , Hans Jörnvall
    • , Hans Hebert
    • , Kristaps Jaudzems
    • , Tore Curstedt
    • , Anna Rising
    •  & Jan Johansson

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