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Breaking up the StayGold dimer yields three photostable monomers

The exceptionally photostable green fluorescent protein StayGold has been monomerized in different laboratories, which has generated three unique monomeric variants that will enable new imaging applications.

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Fig. 1: Compatibility of applications of fluorescent proteins with the aggregation state of the fluorescent protein that is used.

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Correspondence to Joachim Goedhart or Theodorus W. J. Gadella Jr.

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Goedhart, J., Gadella, T.W.J. Breaking up the StayGold dimer yields three photostable monomers. Nat Methods 21, 558–559 (2024). https://doi.org/10.1038/s41592-024-02223-8

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