Featured
-
-
Article
| Open AccessGermline specific genes increase DNA double-strand break repair and radioresistance in lung adenocarcinoma cells
- Wenqing Liu
- , Jan Willem Bruggeman
- & Geert Hamer
-
Article
| Open AccessSingle-cell transcriptional landscape of long non-coding RNAs orchestrating mouse heart development
- Thaís A. R. Ramos
- , Sebastián Urquiza-Zurich
- & Vinicius Maracaja-Coutinho
-
Article
| Open AccessThe long noncoding RNA nHOTAIRM1 is necessary for differentiation and activity of iPSC-derived spinal motor neurons
- Paolo Tollis
- , Erika Vitiello
- & Elisa Caffarelli
-
Article
| Open AccessKindlin-2 in myoepithelium controls luminal progenitor commitment to alveoli in mouse mammary gland
- Zhenbin Wang
- , Lei Zhang
- & Hongquan Zhang
-
Article
| Open AccessKLF4 regulates skeletal muscle development and regeneration by directly targeting P57 and Myomixer
- Shufang Cai
- , Xiaoyu Wang
- & Delin Mo
-
Article
| Open AccessHNF1A binds and regulates the expression of SLC51B to facilitate the uptake of estrone sulfate in human renal proximal tubule epithelial cells
- Jun Wei Chan
- , Claire Wen Ying Neo
- & Adrian Kee Keong Teo
-
Article
| Open AccessUSP18 is an essential regulator of muscle cell differentiation and maturation
- Cyriel Sebastiaan Olie
- , Adán Pinto-Fernández
- & Benedikt M. Kessler
-
Article
| Open AccessTranscriptional and post-transcriptional control of autophagy and adipogenesis by YBX1
- Ruifan Wu
- , Shengchun Feng
- & Qingyan Jiang
-
Article
| Open AccessDiverse maturity-dependent and complementary anti-apoptotic brakes safeguard human iPSC-derived neurons from cell death
- Ruven Wilkens
- , Anne Hoffrichter
- & Philipp Koch
-
Article
| Open AccessLineage-selective super enhancers mediate core regulatory circuitry during adipogenic and osteogenic differentiation of human mesenchymal stem cells
- Chen Wang
- , Wen Tian
- & Yan Guo
-
Article
| Open AccessRNF4~RGMb~BMP6 axis required for osteogenic differentiation and cancer cell survival
- Rostislav Novak
- , Yamen Abu Ahmad
- & Amir Orian
-
Article
| Open AccessDevelopmental modeling of hepatogenesis using obese iPSCs-hepatocyte differentiation uncovers pathological features
- Divya Saro Varghese
- , Thilina T. Alawathugoda
- & Suraiya A. Ansari
-
Article
| Open AccessCannabinoid CB1 receptor gene inactivation in oligodendrocyte precursors disrupts oligodendrogenesis and myelination in mice
- Aníbal Sánchez-de la Torre
- , Tania Aguado
- & Javier Palazuelos
-
Article
| Open AccessLong noncoding RNA ZFP36L2-AS functions as a metabolic modulator to regulate muscle development
- Bolin Cai
- , Manting Ma
- & Qinghua Nie
-
Article
| Open AccessGenome-wide identification of microRNA targets reveals positive regulation of the Hippo pathway by miR-122 during liver development
- Yin Zhang
- , Ye-Ya Tan
- & Liang-Hu Qu
-
Article
| Open AccessSingle-cell transcriptome profiling reveals intratumoural heterogeneity and malignant progression in retinoblastoma
- Jie Yang
- , Yongyun Li
- & Jiayan Fan
-
Article
| Open AccessCHD8 safeguards early neuroectoderm differentiation in human ESCs and protects from apoptosis during neurogenesis
- Song Ding
- , Xianchun Lan
- & Wei Jiang
-
Article
| Open AccessPRMT7 targets of Foxm1 controls alveolar myofibroblast proliferation and differentiation during alveologenesis
- Huacheng He
- , Jilin Chen
- & Qiuling Li
-
Article
| Open AccessSOX10 ablation severely impairs the generation of postmigratory neural crest from human pluripotent stem cells
- Xingqiang Lai
- , Jia Liu
- & Boxiong Jiang
-
Article
| Open AccessHMGB2 orchestrates mitotic clonal expansion by binding to the promoter of C/EBPβ to facilitate adipogenesis
- Keren Chen
- , Junyan Zhang
- & Delin Mo
-
Article
| Open AccessFURIN and placental syncytialisation: a cautionary tale
- Saije K. Morosin
- , Sarah J. Delforce
- & Kirsty G. Pringle
-
Article
| Open AccessKDM4A regulates myogenesis by demethylating H3K9me3 of myogenic regulatory factors
- Qi Zhu
- , Feng Liang
- & Delin Mo
-
Article
| Open AccessCG6015 controls spermatogonia transit-amplifying divisions by epidermal growth factor receptor signaling in Drosophila testes
- Jun Yu
- , Qianwen Zheng
- & Fei Sun
-
Article
| Open AccessBMP2-dependent gene regulatory network analysis reveals Klf4 as a novel transcription factor of osteoblast differentiation
- Shuaitong Yu
- , Jinqiang Guo
- & Zhi Chen
-
Article
| Open AccessCdk5rap3 is essential for intestinal Paneth cell development and maintenance
- Michaela Quintero
- , Siyang Liu
- & Honglin Li
-
Article
| Open AccessPU.1 drives specification of pluripotent stem cell-derived endothelial cells to LSEC-like cells
- Jonathan De Smedt
- , Elise Anne van Os
- & Catherine M. Verfaillie
-
Article
| Open AccessIndoleamine 2,3-dioxygenase 1 limits hepatic inflammatory cells recruitment and promotes bile duct ligation-induced liver fibrosis
- Chan Mo
- , Shuwen Xie
- & Zhiping Lv
-
Article
| Open AccessTRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy
- Huan-Tian Zhang
- , Qingzhong Zeng
- & Xuejuan Gao
-
Article
| Open AccessExosomal arrow (Arr)/lipoprotein receptor protein 6 (LRP6) in Drosophila melanogaster increases the extracellular level of Sol narae (Sona) in a Wnt-independent manner
- Jeong-Hoon Han
- , Yeon Kim
- & Kyung-Ok Cho
-
Article
| Open AccessNLRP7 plays a functional role in regulating BMP4 signaling during differentiation of patient-derived trophoblasts
- Aybuke Alici-Garipcan
- , Burcu Özçimen
- & Nesrin Özören
-
Article
| Open AccessGADD45α drives brown adipose tissue formation through upregulating PPARγ in mice
- Wenjing You
- , Ziye Xu
- & Tizhong Shan
-
Article
| Open AccessHOTAIRM1 regulates neuronal differentiation by modulating NEUROGENIN 2 and the downstream neurogenic cascade
- Jessica Rea
- , Valentina Menci
- & Elisa Caffarelli
-
Article
| Open AccessBCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells
- Larry Sai Weng Loo
- , Andreas Alvin Purnomo Soetedjo
- & Adrian Kee Keong Teo
-
Article
| Open AccessCUEDC2 controls osteoblast differentiation and bone formation via SOCS3–STAT3 pathway
- Jung-Woo Kim
- , Sin-Hye Oh
- & Jeong-Tae Koh
-
Article
| Open AccessHistone deacetylase 1 and 2 drive differentiation and fusion of progenitor cells in human placental trophoblasts
- Gargi Jaju Bhattad
- , Mariyan J. Jeyarajah
- & Stephen J. Renaud
-
Article
| Open Accessp53 controls genomic stability and temporal differentiation of human neural stem cells and affects neural organization in human brain organoids
- Ana Marin Navarro
- , Robin Johan Pronk
- & Margareta Wilhelm
-
Article
| Open AccessTransmissible gastroenteritis virus targets Paneth cells to inhibit the self-renewal and differentiation of Lgr5 intestinal stem cells via Notch signaling
- Aimin Wu
- , Bing Yu
- & Daiwen Chen
-
Article
| Open AccessLoss of PARP-1 attenuates diabetic arteriosclerotic calcification via Stat1/Runx2 axis
- Peng Li
- , Ying Wang
- & Ming-xiang Zhang
-
Article
| Open AccessEpigenetic priming by Dot1l in lymphatic endothelial progenitors ensures normal lymphatic development and function
- Hyunjin Yoo
- , Young Jae Lee
- & Kwonho Hong
-
Article
| Open AccessConcomitant deletion of HRAS and NRAS leads to pulmonary immaturity, respiratory failure and neonatal death in mice
- Rocío Fuentes-Mateos
- , David Jimeno
- & Eugenio Santos
-
Article
| Open AccessPim1 kinase positively regulates myoblast behaviors and skeletal muscle regeneration
- Yuantong Liu
- , Yue Shang
- & Zhenzhong Li
-
Article
| Open AccessExtracellular IL-37 promotes osteogenic differentiation of human bone marrow mesenchymal stem cells via activation of the PI3K/AKT signaling pathway
- Chenyi Ye
- , Wei Zhang
- & Rongxin He
-
Article
| Open AccessSalvador–Warts–Hippo pathway regulates sensory organ development via caspase-dependent nonapoptotic signaling
- Lan-Hsin Wang
- & Nicholas E. Baker
-
Article
| Open AccessThe fine-tuning of endoplasmic reticulum stress response and autophagy activation during trophoblast syncytialization
- Daniel Bastida-Ruiz
- , Lucile Yart
- & Marie Cohen
-
Article
| Open AccessExogenous WNT5A and WNT11 proteins rescue CITED2 dysfunction in mouse embryonic stem cells and zebrafish morphants
- João M. A. Santos
- , Leonardo Mendes-Silva
- & José Bragança
-
Article
| Open AccessDephosphorylation of HDAC4 by PP2A-Bδ unravels a new role for the HDAC4/MEF2 axis in myoblast fusion
- Alexandra Veloso
- , Maud Martin
- & Franck Dequiedt
-
Article
| Open AccessSrlp is crucial for the self-renewal and differentiation of germline stem cells via RpL6 signals in Drosophila testes
- Jun Yu
- , Yidan Yan
- & Jie Fang
-
Article
| Open AccessPlanar cell polarity protein Dishevelled 3 (Dvl3) regulates ectoplasmic specialization (ES) dynamics in the testis through changes in cytoskeletal organization
- Linxi Li
- , Baiping Mao
- & C. Yan Cheng
-
Article
| Open AccessMiR-15b and miR-322 inhibit SETD3 expression to repress muscle cell differentiation
- Meng-Jie Zhao
- , Jun Xie
- & Hai-Ning Du