Combination therapy with optimal doses of multiple antihypertensive drugs fails to achieve blood pressure (BP) control in up to 15% of hypertensive patients. Key studies in 2015 highlighted the risks of uncontrolled hypertension and evaluated new therapeutic modalities designed to achieve satisfactory BP control in patients with treatment-resistant hypertension.
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Acknowledgements
The authors' work is partly supported by NIH grants DK100081, DK73608, HL123160, and DK102325.
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Lerman, L., Textor, S. Resistant hypertension: impact and evolving treatment options. Nat Rev Nephrol 12, 70–72 (2016). https://doi.org/10.1038/nrneph.2015.199
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DOI: https://doi.org/10.1038/nrneph.2015.199