Restrictive transfusion strategy saves blood and is safe in most clinical settings, including gastrointestinal bleeding. However, generalizability of a restrictive transfusion approach in acute gastrointestinal bleeding remains controversial as it often affects elderly patients with major cardiovascular comorbidity who have been excluded from existing trials.
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Villanueva, C. Blood transfusion for acute upper gastrointestinal bleeding. Nat Rev Gastroenterol Hepatol 12, 432–434 (2015). https://doi.org/10.1038/nrgastro.2015.116
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DOI: https://doi.org/10.1038/nrgastro.2015.116