In 2016, four studies were published that provided crucial new information on the endocrine actions of the hormone fibroblast growth factor 21 (FGF21). These studies provide a framework for the nutritional stimuli that regulate FGF21 expression and demonstrate a major role for FGF21 in primates and humans in regulating food intake, macronutrient preference and central reward pathways.
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References
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Acknowledgements
The author's laboratory is supported by the NIH (grant R01DK106104) and the Fraternal Order of Eagles Diabetes Research Center.
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Potthoff, M. A new frontier in FGF21 biology. Nat Rev Endocrinol 13, 74–76 (2017). https://doi.org/10.1038/nrendo.2016.206
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DOI: https://doi.org/10.1038/nrendo.2016.206
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