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Atrial fibrillation

Blockade of the renin–angiotensin system in atrial fibrillation

Nature Reviews Cardiology volume 7, pages 428–430 (2010)Cite this article

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The effectiveness of existing strategies for management of atrial fibrillation is limited, which has stimulated research into novel therapeutic approaches. A new meta-analysis of randomized controlled trials of inhibitors of the renin–angiotensin system highlights the clinical benefits of these agents and underscores their potential in the prevention and treatment of this disease.

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Figure 1: Possible mechanisms by which ACEIs and ARBs prevent AF.

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Authors and Affiliations

  1. Hemostasis Thrombosis and Vascular Biology Unit, University of Birmingham Center for Cardiovascular Sciences, City Hospital, Dudley Road, Birmingham, B18 7QH, UK

    Nadzeya Kuzniatsova, Eduard Shantsila & Gregory Y. H. Lip

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  1. Nadzeya Kuzniatsova
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  2. Eduard Shantsila
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  3. Gregory Y. H. Lip
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Correspondence to Gregory Y. H. Lip.

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Kuzniatsova, N., Shantsila, E. & Lip, G. Blockade of the renin–angiotensin system in atrial fibrillation. Nat Rev Cardiol 7, 428–430 (2010). https://doi.org/10.1038/nrcardio.2010.103

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