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Nature Reviews Cancer 5, 397–405 (1 May 2005) | doi:10.1038/nrc1613

Immunotherapy and chemotherapy |[mdash]| a practical partnership

Richard A. Lake & Bruce W.S. Robinson

This article discusses how recent data have altered the way we understand how dying tumour cells, particularly those killed by chemotherapy, engage with antitumour immune responses. These data have significant implications for the development of new protocols combining chemotherapy with immunotherapy, indicating an exciting potential for therapeutic synergy with general applicability to many cancer types.