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| Editorial |  Top |
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Taking more interest in conflict p713
doi:10.1038/10416
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(18K)
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| Letters to Editor | Top |
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Does cyclosporin A cause cancer? p714
Robert B.M. Landewé, Ben E.E.M. van den Borne, Ferdinand C. Breedveld
& Ben A.C. Dijkmans
doi:10.1038/10417
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(16K)
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Clinical research, or classical clinical research? pp714 - 715
Carl Persson
doi:10.1038/10419
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(26K)
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Oxidative DNA damage and embryo development p715
Ulf J. Eriksson
doi:10.1038/10420
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(19K)
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| News | Top |
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Conflict-of-interest problems lead to policy changes pp717 - 718
Karen Birmingham
& Tinker Ready
doi:10.1038/10421
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(151K)
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Lawsuit reveals academic conflict-of-interest p717
Karen Birmingham
doi:10.1038/10423
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(109K)
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Local people threaten chimp sanctuary p718
Kris Novak
doi:10.1038/10424
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(52K)
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NIH to create PhD program p719
Alan Dove
doi:10.1038/10426
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(47K)
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Bioinformatics an NIH priority pp719 - 720
Marlene Cimons
doi:10.1038/10428
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(81K)
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FDA bans UK blood donation p720
Alicia Ault
doi:10.1038/10429
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(44K)
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Italian clamp-down on fertility research techniques p720
Martina Ballmaier
doi:10.1038/10431
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(44K)
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US to make research marijuana more accessible p721
Marlene Cimons
doi:10.1038/10432
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(61K)
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Student drop-outs cause university ranking fears p721
Rada Rouse
doi:10.1038/10434
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(61K)
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Spain to build new cancer research center p722
Xavier Bosch
doi:10.1038/10435
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(20K)
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Corruption in French research charity p722
Beatrice Renault
doi:10.1038/10436
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(20K)
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Team develops biological computer p722
Victor D. Chase
doi:10.1038/10437
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(20K)
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Thailand to regulate animal provision p722
Robert Triendl
doi:10.1038/10438
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(20K)
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| Commentary | Top |
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Strategies used by human immunodeficiency virus that allow persistent
viral replication pp723 - 725
Ronald C. Desrosiers
doi:10.1038/10439
Abstract | Full text | PDF
(117K)
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| Book Reviews | Top |
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Infections and Inequalities: The Modern Plagues p727
Reviewed by: Michael Marmot
doi:10.1038/10441
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(68K)
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The Development of Human Gene Therapy pp728 - 729
Reviewed by: Elizabeth G. Nabel
doi:10.1038/10443
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(115K)
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Has Feminism Changed Science? p729
Reviewed by: Flossie Wong-Staal
doi:10.1038/10445
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(69K)
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| News and Views | Top |
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Fighting arthritis with a senescence gene pp731 - 732
Dennis A. Carson
& Norio Haneji
doi:10.1038/10447
Abstract | Full text | PDF
(51K)
See also: Article by Taniguchi et al. |
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Cluster headache: Phrenology revisited? pp732 - 733
Cornelius Weiller
& Michel Rijntjes
doi:10.1038/10449
Abstract | Full text | PDF
(53K)
See also: Article by May et al. |
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The matrix delivers pp733 - 734
D.A. Lauffenburger
& D.V. Schaffer
doi:10.1038/10451
Abstract | Full text | PDF
(315K)
See also: Article by Bonadio et al. |
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Two lesions are better than one for spinal cord regeneration p734
Karen Birmingham
doi:10.1038/10453
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(291K)
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Heparanase: Breaking down barriers in tumors pp735 - 736
Suzanne A. Eccles
doi:10.1038/10455
Abstract | Full text | PDF
(159K)
See also: Article by Vlodavsky et al. | Article by Hulett et al. |
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MEK Wars, a new front in the battle against cancer pp736 - 737
Nicholas S. Duesbery, Craig P. Webb
& George F. Vande Woude
doi:10.1038/10457
Abstract | Full text | PDF
(114K)
See also: Article by Sebolt-Leopold et al. |
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Targeting AIDS-Kaposi's sarcoma pp738 - 739
Enrique A. Mesri
doi:10.1038/10459
Abstract | Full text | PDF
(248K)
See also: Article by Husain et al. |
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HIV-1 entry inhibitors: Evading the issue pp740 - 742
Nelson L. Michael
& John P. Moore
doi:10.1038/10462
Abstract | Full text | PDF
(191K)
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Obesity: Autonomic circuits versus feeding pp742 - 743
Katsunori Nonogaki
doi:10.1038/10464
Abstract | Full text | PDF
(48K)
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| Review | Top |
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Integration of endoplasmic reticulum signaling in health and disease pp745 - 751
Meir Aridor
& William E. Balch
doi:10.1038/10466
Abstract | Full text | PDF
(164K)
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| Articles | Top |
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Localized, direct plasmid gene delivery in vivo: prolonged therapy
results in reproducible tissue regeneration pp753 - 759
Jeffrey Bonadio, Elizabeth Smiley, Pravin Patil
& Steven Goldstein
doi:10.1038/10473
Abstract | Full text | PDF
(1,629K)
See also: News and Views by Lauffenburger & Schaffer |
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Induction of the p16INK4a senescence gene as a new therapeutic
strategy for the treatment of rheumatoid arthritis pp760 - 767
Ken Taniguchi, Hitoshi Kohsaka, Naoki Inoue, Yoshio Terada, Hiroshi Ito, Katsuiku Hirokawa
& Nobuyuki Miyasaka
doi:10.1038/10480
Abstract | Full text | PDF
(584K)
See also: News and Views by Carson & Haneji |
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Long-term cure of the photosensitivity of murine erythropoietic protoporphyria
by preselective gene therapy pp768 - 773
Robert Pawliuk, Thomas Bachelot, Robert J. Wise, Micheline M. Mathews-Roth
& Philippe Leboulch
doi:10.1038/10488
Abstract | Full text | PDF
(381K)
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CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic
T-lymphocyte tolerance and augments anti-tumor vaccine efficacy pp774 - 779
Linda Diehl, Annemieke Th. den Boer, Stephen P. Schoenberger, Ellen I.H. van der Voort, Ton N.M. Schumacher, Cornelis J.M. Melief, Rienk Offringa
& Rene E. M. Toes
doi:10.1038/10495
Abstract | Full text | PDF
(90K)
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Conversion of tumor-specific CD4+ T-cell tolerance to
T-cell priming through in vivo ligation of CD40 pp780 - 787
Eduardo M. Sotomayor, Ivan Borrello, Erev Tubb, Frédérique-Marie Rattis, Harold Bien, Zhengbin Lu, Steve Fein, Stephen Schoenberger
& Hyam I. Levitsky
doi:10.1038/10503
Abstract | Full text | PDF
(393K)
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Protective effects of C5a blockade in sepsis pp788 - 792
Boris J. Czermak, Vidya Sarma, Carl L. Pierson, Roscoe L. Warner, Markus Huber-Lang, Nicolas M. Bless, Hagen Schmal, Hans Peter Friedl
& Peter A. Ward
doi:10.1038/10512
Abstract | Full text | PDF
(69K)
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Mammalian heparanase: Gene cloning, expression and function in tumor
progression and metastasis pp793 - 802
Israel Vlodavsky, Yael Friedmann, Michael Elkin, Helena Aingorn, Ruth Atzmon, Rivka Ishai-Michaeli, Menachem Bitan, Orit Pappo, Tuvia Peretz, Israel Michal, Larissa Spector
& Iris Pecker
doi:10.1038/10518
Abstract | Full text | PDF
(711K)
See also: News and Views by Eccles | Article by Hulett et al. |
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Cloning of mammalian heparanase, an important enzyme in tumor invasion
and metastasis pp803 - 809
Mark D. Hulett, Craig Freeman, Brenton J. Hamdorf, Rohan T. Baker, Matthew J. Harris
& Christopher R. Parish
doi:10.1038/10525
Abstract | Full text | PDF
(213K)
See also: News and Views by Eccles | Article by Vlodavsky et al. |
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Blockade of the MAP kinase pathway suppresses growth of colon tumors
in vivo pp810 - 816
Judith S. Sebolt-Leopold, David T. Dudley, Roman Herrera, Keri Van Becelaere, Amy Wiland, Richard C. Gowan, Haile Tecle, Stephen D. Barrett, Alexander Bridges, Sally Przybranowski, W.R. Leopold
& Alan R. Saltiel
doi:10.1038/10533
Abstract | Full text | PDF
(386K)
See also: News and Views by Duesbery et al. |
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Interleukin-4 receptor-directed cytotoxin therapy of AIDS-associated
Kaposi's sarcoma tumors in xenograft model pp817 - 822
Syed R. Husain, Robert J. Kreitman, Ira Pastan
& Raj K. Puri
doi:10.1038/10541
Abstract | Full text | PDF
(77K)
See also: News and Views by Mesri |
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Cancer therapy using a self-replicating RNA vaccine pp823 - 827
Han Ying, Tal Z. Zaks, Rong-Fu Wang, Kari R. Irvine, Udai S. Kammula, Francesco M. Marincola, Wolfgang W. Leitner
& Nicholas P. Restifo
doi:10.1038/10548
Abstract | Full text | PDF
(115K)
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Mice deficient in tumor necrosis factor- are resistant to skin
carcinogenesis pp828 - 831
Robert J. Moore, David M. Owens, Gordon Stamp, Caroline Arnott, Frances Burke, Nick East, Hazel Holdsworth, Lynn Turner, Barrett Rollins, Manolis Pasparakis, George Kollias
& Frances Balkwill
doi:10.1038/10552
Abstract | Full text | PDF
(186K)
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Inhibition of virus-induced neuronal apoptosis by Bax pp832 - 835
Jennifer Lewis, George A. Oyler, Kazuyoshi Ueno, Yih-Ru Fannjiang, B. Nelson Chau, James Vornov, Stanley J. Korsmeyer, Shifa Zou
& J. Marie Hardwick
doi:10.1038/10556
Abstract | Full text | PDF
(503K)
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Correlation between structural and functional changes in brain in an
idiopathic headache syndrome pp836 - 838
A. May, J. Ashburner, C. Büchel, D.J. McGonigle, K.J. Friston, R.S.J. Frackowiak
& P.J. Goadsby
doi:10.1038/10561
Abstract | Full text | PDF
(396K)
See also: News and Views by Weiller & Rijntjes |
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Tetrameric HLA class I−minor histocompatibility antigen peptide
complexes demonstrate minor histocompatibility antigen-specific cytotoxic
T lymphocytes in patients with graft-versus-host disease pp839 - 842
Tuna Mutis, Geraldine Gillespie, Ellen Schrama, J.H. Frederik Falkenburg, Paul Moss
& Els Goulmy
doi:10.1038/10563
Abstract | Full text | PDF
(65K)
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| New Technology | Top |
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Gene transfer into CD4+ T lymphocytes: Green fluorescent
protein-engineered, encephalitogenic T cells illuminate brain autoimmune responses pp843 - 847
Alexander Flügel, Michael Willem, Tomasz Berkowicz
& Hartmut Wekerle
doi:10.1038/10567
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(820K)
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| ON THE MARKET pp847 - 848Full text | PDF
(256K)
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| Errata | Top |
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Ultraviolet irradiation of human skin causes functional vitamin A deficiency, preventable by all-trans retinoic acid pre-treatment p849
Z. Wang, M. Boudjelal, S. Kang, J.J. Voorhees
& G.J. Fisher
doi:10.1038/10577
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(115K)
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Calpain 3 deficiency is associated with myonuclear apoptosis and profound
perturbation of the IkBa/NF-kB pathway in limb-girdle muscular dystrophy type
2A p849
S. Baghdiguian, M. Martin, I. Richard, F. Pons, C. Astier, N. Bourg, R.T. Hay, R. Chemaly, G. Halaby, J. Loiselet, L.V.B. Anderson, A. Lopez de Munain, M. Fardeau, P. Mangeat, J.S. Beckmann
& G. Lefranc
doi:10.1038/10579
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Inhibition of HIV replication by dominant negative mutants of Sam68, a functional homolog of HIV-1 Rev p849
T.R. Reddy, W. Xu, J.K.L. Mau, C.D. Goodwin, M. Suhasini, H. Tang, K. Frimpong, D.W. Rose
& F. Wong-Staal
doi:10.1038/10581
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(115K)
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News & Views figures p849
doi:10.1038/11134
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