As it becomes evident that the microbiome exerts an influence on the human immune system, scientists have begun to ponder therapies that might act on intestinal microbes to reduce harmful inflammation. Roxanne Khamsi reports.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Brestoff, J.R. & Artis, D. Nat Immunol. 14, 676–684 (2013).
Trompette, A. et al. Nat. Med. 20, 159–166 (2014).
Scheppach, W. et al. Gastroenterology 103, 51–56 (1992).
O'Keefe, S.J.D. et al. Nat. Commun. 6, 6342 (2015).
Wall, R., Ross, R.P., Fitzgerald, G.F. & Stanton, C. Nutr. Rev. 68, 280–289 (2010).
Liou, A.P. et al. Sci. Trans. Med. 5, doi: 10.1126/scitranslmed.3005687 (2013).
Arribas, B. et al. Br. J. Pharmacol. 157, 1024–1033 (2009).
Becker, H.M., Apladas, A., Scharl, M., Fried, M. & Rogler, G. Digestion 82, 110–118 (2014).
Atarashi, K. et al. Nature 500, 232–236 (2013).
Tang, W.H. et al. J. Card. Fail. 21, 91–96 (2015).
Wang, Z. et al. Nature 472, 57–63 (2011).
Gregory, J.C. et al. J. Biol. Chem. 290, 5647–5660 (2015).
Scorletti, E. et al. Hepatology 60, 1211–1221 (2014).
Lukens, J.R. et al. Nature 516, 246–249 (2014).
Trompette, A. et al. Nat. Med. 20, 159–166 (2014).
Vieira, A.T. et al. Arthritis Rheumatol. 67, 1646–1656 (2015).
You, J., Dong, H., Mann, E.R., Knight, S.C. & Yaqoob, P. Immunobiology 219, 138–148 (2014).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Khamsi, R. A gut feeling about immunity. Nat Med 21, 674–676 (2015). https://doi.org/10.1038/nm.3906
Published:
Issue Date:
DOI: https://doi.org/10.1038/nm.3906