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Cooperative regulatory events and Foxp3 expression

Nature Immunology volume 12, pages 14–16 (2011)Cite this article

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The molecular mechanisms that control Treg and TH17 development and the precise role of TGF-β in this process are complex and imperfectly understood. New findings indicate that the helix-loop-helix proteins E2A and Id3 are also critically involved in some of these processes.

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Figure 1: Transcriptional regulation of Foxp3.

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Author notes

  1. masahide.tone@csmc.edu

Authors and Affiliations

  1. Masahide Tone is in the Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA.,

    Masahide Tone

  2. Mark I. Greene is in the Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.,

    Mark I Greene

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  1. Masahide Tone
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  2. Mark I Greene
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Tone, M., Greene, M. Cooperative regulatory events and Foxp3 expression. Nat Immunol 12, 14–16 (2011). https://doi.org/10.1038/ni0111-14

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