TABLE OF CONTENTS
Volume 17, Issue 7 (July 2003)
Review |
Molecular Targets for Therapys (MTT) |
Original Manuscripts |
Biotechnical Methods Section (BTS) |
Method in Focus |
Spotlight Correspondence |
Correspondence
Opinions and Ideas
The adult hemopoietic stem cell plasticity debate: idols vs new paradigms FREE
B E Moore and P J Quesenberry
Leukemia 17: 1205-1210; doi:10.1038/sj.leu.2402956
Review
Chronic myelogenous leukemia as a paradigm of early cancer and possible curative strategies FREE
B Clarkson, A Strife, D Wisniewski, C L Lambek and C Liu
Leukemia 17: 1211-1262; doi:10.1038/sj.leu.2402912
Molecular Targets for Therapys (MTT)
Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention FREE
F Chang, L S Steelman, J T Lee, J G Shelton, P M Navolanic, W L Blalock, R A Franklin and J A McCubrey
Leukemia 17: 1263-1293; doi:10.1038/sj.leu.2402945
Effects of inhibitors of the chemokine receptor CXCR4 on acute lymphoblastic leukemia cells in vitro FREE
J Juarez, K F Bradstock, D J Gottlieb and L J Bendall
Leukemia 17: 1294-1300; doi:10.1038/sj.leu.2402998
WT1 in acute leukemia, chronic myelogenous leukemia and myelodysplastic syndrome: therapeutic potential of WT1 targeted therapies FREE
C Rosenfeld, M A Cheever and A Gaiger
Leukemia 17: 1301-1312; doi:10.1038/sj.leu.2402988
Original Manuscripts
Chronic Myeloid Leukemia
Quantitative PCR identifies a minimal deleted region of 120 kb extending from the Philadelphia chromosome ABL translocation breakpoint in chronic myeloid leukemia with poor outcome FREE
E Kolomietz, P Marrano, K Yee, B Thai, I Braude, A Kolomietz, K Chun, S Minkin, S Kamel-Reid, M Minden and J A Squire
Leukemia 17: 1313-1323; doi:10.1038/sj.leu.2402969
B-Acute Lymphoblastic Leukemia and Diagnosis
DNA microarrays for comparison of gene expression profiles between diagnosis and relapse in precursor-B acute lymphoblastic leukemia: choice of technique and purification influence the identification of potential diagnostic markers FREE
F J T Staal, M van der Burg, L F A Wessels, B H Barendregt, M R M Baert, C M M van den Burg, C Van Huffel, A W Langerak, V H J van der Velden, M J T Reinders and J J M van Dongen
Leukemia 17: 1324-1332; doi:10.1038/sj.leu.2402974
Acute Promyelocytic Leukemia and AS203
Arsenic trioxide-induced mitotic arrest and apoptosis in acute promyelocytic leukemia cells FREE
X Cai, Y Yu, Y Huang, L Zhang, P-M Jia, Q Zhao, Z Chen, J-H Tong, W Dai and G-Q Chen
Leukemia 17: 1333-1337; doi:10.1038/sj.leu.2402983
Sensitivity and Resistance to Leukemia
In vitro cytotoxicity of aplidin and crossresistance with other cytotoxic drugs in childhood leukemic and normal bone marrow and blood samples: a rational basis for clinical development FREE
D Bresters, A J F Broekhuizen, P Kaaijk, G T Faircloth, J Jimeno and G J L Kaspers
Leukemia 17: 1338-1343; doi:10.1038/sj.leu.2402972
Dose reduction of coadministered 6-mercaptopurine decreases myelotoxicity following high-dose methotrexate in childhood leukemia FREE
U Nygaard and K Schmiegelow
Leukemia 17: 1344-1348; doi:10.1038/sj.leu.2402990
Apotosis
NF-
B2/p100 induces Bcl-2 expression FREE
P Viatour, M Bentires-Alj, A Chariot, V Deregowski, L de Leval, M-P Merville and V Bours
Leukemia 17: 1349-1356; doi:10.1038/sj.leu.2402982
Apoptosis
Mitochondria control of cell death induced by anti-HLA-DR antibodies FREE
S K Bains, A Mone, J Yun Tso, D Lucas, J C Byrd, G J Weiner and J M Green
Leukemia 17: 1357-1365; doi:10.1038/sj.leu.2402976
Stemcellology
Differential response of primitive human CD34- and CD34+ hematopoietic cells to the Notch ligand Jagged-1 FREE
F N Karanu, L Yuefei, L Gallacher, S Sakano and M Bhatia
Leukemia 17: 1366-1374; doi:10.1038/sj.leu.2402973
Stem Cell Transplantation
Ex vivo purging of leukemia cells using tumor-necrosis-factor-related apoptosis-inducing ligand in hematopoietic stem cell transplantation FREE
N-S Lee, H-J Cheong, S-J Kim, S-E Kim, C-K Kim, K-T Lee, S-K Park, S-H Baick, D-S Hong, H-S Park and J-H Won
Leukemia 17: 1375-1383; doi:10.1038/sj.leu.2402960
Immunobiology
A cholesterol-dependent CD20 epitope detected by the FMC7 antibody FREE
M J Polyak, L M Ayer, A J Szczepek and J P Deans
Leukemia 17: 1384-1389; doi:10.1038/sj.leu.2402978
Lymphoma
The BCL6 gene in B-cell lymphomas with 3q27 translocations is expressed mainly from the rearranged allele irrespective of the partner gene FREE
I S Lossos, T Akasaka, J A Martinez-Climent, R Siebert and R Levy
Leukemia 17: 1390-1397; doi:10.1038/sj.leu.2402997
Myeloma
Incomplete DJH rearrangements of the IgH gene are frequent in multiple myeloma patients: immunobiological characteristics and clinical implications FREE
D González, A Balanzategui, R García-Sanz, N Gutiérrez, C Seabra, J J M van Dongen, M González and J F San Miguel
Leukemia 17: 1398-1403; doi:10.1038/sj.leu.2402964
Biotechnical Methods Section (BTS)
BARCODE-ALL: accelerated and cost-effective genetic risk stratification in acute leukemia using spectrally addressable liquid bead microarrays FREE
J Wallace, Y Zhou, G N Usmani, M Reardon, P Newburger, B Woda and G Pihan
Leukemia 17: 1404-1410; doi:10.1038/sj.leu.2402985
Method in Focus
BARCODE-ALL: accelerated and cost-effective genetic risk stratification in acute leukemia using spectrally addressable liquid bead microarrays FREE
J Wallace, Y Zhou, G N Usmani, M Reardon, P Newburger, B Woda and G Pihan
Leukemia 17: 1411-1413; doi:10.1038/sj.leu.2402986
Spotlight Correspondence
Dose-limiting dermatological toxicity secondary to imatinib mesylate (STI571) in chronic myeloid leukaemia FREE
D Milojkovic, K Short, J R Salisbury, D Creamer, A W P du Vivier and G J Mufti
Leukemia 17: 1414-1416; doi:10.1038/sj.leu.2402991
Correspondence
Radiation recall phenomenon associated with arsenic trioxide FREE
Y-K Keung, E S Lyerly and B L Powell
Leukemia 17: 1417-1418; doi:10.1038/sj.leu.2402992
Acute promyelocytic leukemia and aural recurrence: the importance of otoscopy in early diagnosis FREE
G Magliulo, M Fusconi and G Pulice
Leukemia 17: 1418-1419; doi:10.1038/sj.leu.2402987
Molecular cytogenetics of polycythaemia vera: lack of occult rearrangements detectable by 20q LSP screening, CGH, and M-FISH FREE
S M Gribble, A G Reid, A J Bench, B J P Huntly, C Grace, A R Green and E P Nacheva
Leukemia 17: 1419-1421; doi:10.1038/sj.leu.2402980
AML1 overexpression and/or mutations should be checked in trisomy 21 patients with megakaryocytic leukemia FREE
J L Huret and C Léonard
Leukemia 17: 1421; doi:10.1038/sj.leu.2402984
A novel TPMT missense mutation associated with TPMT deficiency in a 5-year-old boy with ALL FREE
E Schaeffeler, M Stanulla, J Greil, M Schrappe, M Eichelbaum, U M Zanger and M Schwab
Leukemia 17: 1422-1424; doi:10.1038/sj.leu.2402981
Vaccination of chronic myeloid leukemia patients with autologous in vitro cultured leukemic dendritic cells FREE
G J Ossenkoppele, A G M Stam, T M Westers, T D de Gruijl, J J W M Janssen, A A van de Loosdrecht and R J Scheper
Leukemia 17: 1424-1426; doi:10.1038/sj.leu.2402979
Simultaneous occurrence of chronic myeloid leukemia and multiple myeloma: Evaluation by FISH analysis and in vitro expansion of bone marrow cells FREE
J D Schwarzmeier, M Shehata, J Ackermann, M Hilgarth, H Kaufmann and J Drach
Leukemia 17: 1426-1428; doi:10.1038/sj.leu.2402971
Tryptase-positive mast cells correlate positively with bone marrow angiogenesis in B-cell chronic lymphocytic leukemia FREE
D Ribatti, S Molica, A Vacca, B Nico, E Crivellato, A M Roccaro and F Dammacco
Leukemia 17: 1428-1430; doi:10.1038/sj.leu.2402970
Stage-specific alterations in serum levels of G-CSF in chronic myeloid leukaemia FREE
H G Jørgensen, E K Allan, X Jiang, E Liakopoulou, L Richmond, C J Eaves, A C Eaves and T L Holyoake
Leukemia 17: 1430-1432; doi:10.1038/sj.leu.2402967
MLL AT-hook sequence is strongly conserved in infant acute leukemia with or without MLL gene rearrangement FREE
C M T Macrini, M S Pombo-de-Oliveira, A M Ford and G Alves
Leukemia 17: 1432-1433; doi:10.1038/sj.leu.2402966
Low frequency of bcl-2 rearrangement in HCV-associated non-Hodgkin's lymphoma tissue FREE
Massimo Libra, Valli De Re, Salvatore De Vita, Daniela Gasparotto, Annunziata Gloghini, Maurizio Rupolo, Massimo Degan, Alessandra Marzotto, Franca Stivala, Antonino Carbone and Mauro Boiocchi
Leukemia 17: 1433-1436; doi:10.1038/sj.leu.2402968
