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Tryptase-positive mast cells correlate positively with bone marrow angiogenesis in B-cell chronic lymphocytic leukemia

Leukemia volume 17, pages 1428–1430 (2003)Cite this article

TO THE EDITOR

The importance of angiogenesis for growth and viability of solid tumors has been established. Knowledge on these relations in hematological tumors, however, is circumstantial. Tumor microvessel density predicts a risk of progression in multiple myeloma,1 is correlated with progression stages in both B-cell non-Hodgkin's lymphomas2 and matches in step with the growth of acute leukemias and myelodysplastic syndromes.

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Figure 1

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Acknowledgements

This work was supported in part by grants from Associazione Italiana per la Ricerca sul Cancro (AIRC, Milan) and from Ministero dell'Istruzione, Università e Ricerca (MIUR, Rome), Italy.

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Authors and Affiliations

  1. Department of Human Anatomy and Histology, Bari, Italy

    D Ribatti & B Nico

  2. Department of Hematology-Oncology, Azienda Ospedaliera ‘Pugliese-Ciaccio’, Catanzaro, Italy

    S Molica

  3. Department of Biomedical Sciences and Human Oncology, Section of Internal Medicine and Clinical Oncology, University of Bari Medical School, Bari, Italy

    A Vacca, A M Roccaro & F Dammacco

  4. Department of Medical and Morphological Research, Section of Anatomy, University of Udine Medical School, Udine, Italy

    E Crivellato

Authors
  1. D Ribatti
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  2. S Molica
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  3. A Vacca
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  5. E Crivellato
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  6. A M Roccaro
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  7. F Dammacco
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Correspondence to D Ribatti.

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Ribatti, D., Molica, S., Vacca, A. et al. Tryptase-positive mast cells correlate positively with bone marrow angiogenesis in B-cell chronic lymphocytic leukemia. Leukemia 17, 1428–1430 (2003). https://doi.org/10.1038/sj.leu.2402970

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  • DOI: https://doi.org/10.1038/sj.leu.2402970

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