Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Nanopores

Tiny holes with great promise

Sensors that combine solid-state nanopores and nanowire field-effect transistors can be used to detect single DNA molecules quickly and with high sensitivity.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Detection of DNA translocation with a nanowire–nanopore sensor.

References

  1. Zwolak, M. & Di Ventra, M. Rev. Mod. Phys. 80, 141–165 (2008).

    Article  Google Scholar 

  2. Branton, D. et al. Nature Biotech. 26, 1146–1153 (2008).

    Article  CAS  Google Scholar 

  3. Venkatesan, B. M. & Bashir, R. Nature Nanotech. 6, 615–624 (2011).

    Article  CAS  Google Scholar 

  4. Service, R. F. Science 311, 1544–1546 (2006).

    Article  CAS  Google Scholar 

  5. http://www-03.ibm.com/press/us/en/pressrelease/32037.wss

  6. Levene, M. J. et al. Science 299, 682–686 (2003).

    Article  CAS  Google Scholar 

  7. Eid, J. et al. Science 323, 133–138 (2009).

    Article  CAS  Google Scholar 

  8. Kasianowicz, J. J. et al. Proc. Natl Acad. Sci. USA 93, 13770–13773 (1996).

    Article  CAS  Google Scholar 

  9. Meller, A. et al. Proc. Natl Acad. Sci. USA 97, 1079–1084 (2000).

    Article  CAS  Google Scholar 

  10. Derrington, I. M. et al. Proc. Natl Acad. Sci. USA 107, 16060–16065 (2010).

    Article  CAS  Google Scholar 

  11. Dekker, C. Nature Nanotech. 2, 209–215 (2007).

    Article  CAS  Google Scholar 

  12. Zwolak, M. & Di Ventra, M. Nano Lett. 5, 421–424 (2005).

    Article  CAS  Google Scholar 

  13. Luan, B. et al. Phys. Rev. Lett. 104, 238103 (2010).

    Article  Google Scholar 

  14. Xie, P., Xiong, Q., Fang, Y., Qing, Q. & Lieber, C. M. Nature Nanotech. 7, 119–125 (2012).

    Article  CAS  Google Scholar 

  15. Osaki, T., Suzuki, H., Le Pioufle, B. & Takeuchi, S. Anal. Chem. 81, 9866–9870 (2009).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Dario Anselmetti.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Anselmetti, D. Tiny holes with great promise. Nature Nanotech 7, 81–82 (2012). https://doi.org/10.1038/nnano.2012.11

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nnano.2012.11

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing