FOCUS
EPIGENETICS AND CHROMATIN
- Special issue:
- March 2011 Volume 21, No 3
Epigenetic control refers to the control of expression of genetic information at levels other than the DNA sequence itself, and plays fundamental roles in biological processes such as cell fate determination, development, and disease pathogenesis. The March 2011 Special Issue on Epigenetics & Chromatin brings us a collection of authoritative reviews on diverse topics in this rapidly evolving field. The accompanying web focus presents additional links to related articles in this area from across Nature Publishing Group.
Review
Readers of histone modifications FREE
Miyong Yun, Jun Wu, Jerry L Workman and Bing Li
Cell Res 21: 564-578; advance online publication, March 22, 2011; doi:10.1038/cr.2011.42
Articles
Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures Open
Bin-Kuan Chou, Prashant Mali, Xiaosong Huang, Zhaohui Ye, Sarah N Dowey, Linda MS Resar, Chunlin Zou, Y Alex Zhang, Jay Tong & Linzhao Cheng
Cell Res advance online publication, January 18, 2011; doi:10.1038/cr.2011.12
Role of H3K27 methylation in the regulation of lncRNA expression FREE
Susan C Wu, Eric M Kallin & Yi Zhang
Cell Res 20: 1109-1116; advance online publication, August 3, 2010; doi:10.1038/cr.2010.114
Coordinated regulation of active and repressive histone methylations by a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans FREE
Hanqing Lin, Yiqin Wang, Yanru Wang, Feng Tian, Pu Pu, Yi Yu, Hailei Mao, Ying Yang, Ping Wang, Lulu Hu, Yan Lin, Yi Liu, Yanhui Xu & Charlie Degui Chen
Cell Res 20: 899-907; advance online publication, June 22, 2010; doi:10.1038/cr.2010.84
Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans FREE
Ying Yang, Lulu Hu, Ping Wang, Haifeng Hou, Yan Lin, Yi Liu, Ze Li, Rui Gong, Xiang Feng, Lu Zhou, Wen Zhang, Yuhui Dong, Huirong Yang, Hanqing Lin, Yiqin Wang, Charlie Degui Chen & Yanhui Xu
Cell Res 20: 886-898; advance online publication, June 22, 2010; doi:10.1038/cr.2010.86
Dual-specificity histone demethylase KIAA1718 (KDM7A) regulates neural differentiation through FGF4 FREE
Chengyang Huang, Yang Xiang, Yanru Wang, Xia Li, Longyong Xu, Ziqi Zhu, Ting Zhang, Qingqing Zhu, Kejing Zhang, Naihe Jing & Charlie Degui Chen
Cell Res 20: 154-165; advance online publication, January 19, 2010; doi:10.1038/cr.2010.5
Epigenetic memory in induced pluripotent stem cells
K. Kim, A. Doi, B. Wen, K. Ng, R. Zhao, P. Cahan, J. Kim, M. J. Aryee, H. Ji, L. I. R. Ehrlich, A. Yabuuchi, A. Takeuchi, K. C. Cunniff, H. Hongguang, S. Mckinney-Freeman, O. Naveiras, T. J. Yoon, R. A. Irizarry, N. Jung, J. Seita, J. Hanna, P. Murakami, R. Jaenisch, R. Weissleder, S. H. Orkin, I. L. Weissman, A. P. Feinberg & G. Q. Daley
Nature 467: 285-290; published, September 16, 2010; doi:10.1038/nature09342
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
Shinsuke Ito, Ana C. D’Alessio, Olena V. Taranova, Kwonho Hong, Lawrence C. Sowers & Yi Zhang
Nature 466: 1129-1133; published, August 26, 2010; doi:10.1038/nature09303
Chromatin regulation by Brg1 underlies heart muscle development and disease
Calvin T. Hang, Jin Yang, Pei Han, Hsiu-Ling Cheng, Ching Shang, Euan Ashley, Bin Zhou & Ching-Pin Chang
Nature 466: 62-67; published, July 01, 2010; doi:10.1038/nature09130
An RNA polymerase II- and AGO4-associated protein acts in RNA-directed DNA methylation
Zhihuan Gao, Hai-Liang Liu, Lucia Daxinger, Olga Pontes, Xinjian He, Weiqiang Qian, Huixin Lin, Mingtang Xie, Zdravko J. Lorkovic, Shoudong Zhang, Daisuke Miki, Xiangqiang Zhan, Dominique Pontier, Thierry Lagrange, Hailing Jin, Antonius J. M. Matzke, Marjori Matzke, Craig S. Pikaard & Jian-Kang Zhu
Nature 465: 106-109; published, May 06, 2010; doi:10.1038/nature09025
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency
Christian Popp, Wendy Dean, Suhua Feng, Shawn J. Cokus, Simon Andrews, Matteo Pellegrini, Steven E. Jacobsen & Wolf Reik
Nature 463: 1101-1105; published, February 25, 2010; doi:10.1038/nature08829
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