Collection 

Systemic lupus erythematosus

The pace of research in systemic lupus erythematosus (SLE) has accelerated greatly in recent years, and many new therapeutic agents are showing promise in early clinical trials. This collection of articles from Nature Reviews Rheumatology, Nature Reviews Nephrology and Nature Reviews Disease Primers highlights progress in basic, translational and clinical research in SLE, including new insights into pathogenesis and identifying novel targets for therapy. The collection includes recent Reviews and relevant News and Opinion articles written by leading researchers in the field. It also includes a PrimeView, which summarizes the main features of SLE.

PrimeView: Systemic lupus erythematosus

Nature Reviews Disease Primers

Systemic lupus erythematosus (SLE) is a potentially fatal, chronic autoimmune disorder. This PrimeView illustrates that SLE is heterogeneous with considerable variability in clinical manifestations and disease severity. Early diagnosis and prevention of flares is important to reduce long-term morbidity and mortality.