Collection 

Genomic instability and cancer

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Open
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Genomic instability is characterized by a high frequency of genetic mutations and can manifest as chromosomal copy number aberrations, rearrangements, or smaller alterations. Genomic instability can have pathogenic effects in cancer, and understanding the underlying causes of genomic instability is necessary for developing strategies to reduce and reverse these effects. Additionally, because genomic instability is a characteristic of cancer cells, it is an attractive therapeutic target for anticancer therapy.

This Collection invites original research into genomic instability in cancer, from basic research assessing the underlying mechanisms to preclinical and clinical studies targeting genomic instability.

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Colorful DNA molecule.

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Collections articles undergo Scientific Reports' standard peer review process and are subject to all of the journal’s standard policies. This includes the journal’s policy on competing interests. The Guest Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Guest Editors have competing interests is handled by another Editorial Board Member who has no competing interests. For more information, refer to our Collections guidelines

This Collection has not been supported by sponsorship.