Genomic instability and cancer
- Submission status
- Open
- Submission deadline
Genomic instability is characterized by a high frequency of genetic mutations and can manifest as chromosomal copy number aberrations, rearrangements, or smaller alterations. Genomic instability can have pathogenic effects in cancer, and understanding the underlying causes of genomic instability is necessary for developing strategies to reduce and reverse these effects. Additionally, because genomic instability is a characteristic of cancer cells, it is an attractive therapeutic target for anticancer therapy.
This Collection invites original research into genomic instability in cancer, from basic research assessing the underlying mechanisms to preclinical and clinical studies targeting genomic instability.
Editors
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Xingzhi Xu, PhD, Professor
Shenzhen University Medical School, China
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Yasunaga Yoshikawa, DVM, PhD
Kitasato University, Japan
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Ken-ichi Yoshioka, PhD
National Cancer Center Research Institute, Japan
