Biomarkers for Parkinson’s disease are critical to our efforts to identify disease-modifying therapies. Kern et al. document potential microRNA (miRNA) biomarkers and trends in miRNA regulation that occur in a bimodal distribution with age.
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References
Stocchi, F. & Olanow, C. W. Movement Disord. 28, 3–7 (2013).
Kern, F. et al. Nat. Aging https://doi.org/10.1038/s43587-021-00042-6 (2021).
Marek, K. et al. Ann. Clin. Transl. Neur. 5, 1460–1477 (2018).
Rosenthal, L. S. et al. Movement Disord. 31, 915–923 (2016).
Mohammadi, D. Lancet Neurol. 12, 739–740 (2013).
Martins, M. et al. PLoS ONE 6, e25443 (2011).
Caggiu, E. et al. eNeurologicalSci 13, 1–4 (2018).
Chi, J. et al. Front. Aging Neurosci. 10, 178 (2018).
Ravanidis, S. et al. Ann. Clin. Transl. Neur. 7, 1594–1607 (2020).
Ferguson, L. W., Rajput, A. H. & Rajput, A. Can. J. Neurol. Sci. 43, 113–119 (2016).
Mehanna, R. et al. Parkinsonism Relat. D. 20, 530–534 (2014).
Goodsaid, F. M. & Mendrick, D. L. Sci. Transl. Med. 2, 47ps44 (2010).
List of qualified biomarkers. U.S. Food and Drug Administration https://www.fda.gov/drugs/biomarker-qualification-program/list-qualified-biomarkers (2021).
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Rosenthal, L.S., Yang, J. & Mao, X. Dysregulated miRNAs mark Parkinson’s disease progression. Nat Aging 1, 241–242 (2021). https://doi.org/10.1038/s43587-021-00046-2
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DOI: https://doi.org/10.1038/s43587-021-00046-2