Of the few known catalytic RNAs in biology, all but the ribosome involve reactions with phosphodiester bonds. Now, a ribozyme that catalyses a completely different reaction was discovered in all three domains of life.
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Müller, U.F. RNA-catalysed guanosine methylation. Nat Catal 4, 812–813 (2021). https://doi.org/10.1038/s41929-021-00690-2
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DOI: https://doi.org/10.1038/s41929-021-00690-2
