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IMMUNOLOGY

Finally: development of humanized lymph nodes

Nature Methods volume 15, pages 580–582 (2018)Cite this article

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Overexpression of mouse thymic-stromal-cell-derived lymphopoietin in immune-compromised mice that harbor a reconstituted human immune system rescues lymph node formation and enhances adaptive immune responses.

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Fig. 1: A humanized mouse model with functional lymph nodes (LN).

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Authors and Affiliations

  1. Department of Medical Oncology and Hematology, Division of Hematology, University of Zurich and University Hospital Zurich, Zurich, Switzerland

    Alexandre P. A. Theocharides & Markus G. Manz

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  1. Alexandre P. A. Theocharides
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  2. Markus G. Manz
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Correspondence to Markus G. Manz.

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The authors declare no competing interests.

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Theocharides, A.P.A., Manz, M.G. Finally: development of humanized lymph nodes. Nat Methods 15, 580–582 (2018). https://doi.org/10.1038/s41592-018-0080-5

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