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THYMOCYTE EPIGENOMICS

TCF-1 takes HEB up a Notch

Nature Immunology volume 19, pages 1283–1285 (2018)Cite this article

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Transcription factors orchestrate stage-specific gene expression during development. Two such factors, TCF-1 and HEB, collaborate at the protein and genomic levels to regulate gene expression in developing thymocytes.

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Fig. 1: Multiple levels of cooperation between TCF-1 and HEB.

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Authors and Affiliations

  1. Laboratory of Genome Integrity, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA

    Christelle Harly

  2. Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA

    Thomas Ciucci

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  1. Christelle Harly
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  2. Thomas Ciucci
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Correspondence to Thomas Ciucci.

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The authors declare no competing interests.

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Harly, C., Ciucci, T. TCF-1 takes HEB up a Notch. Nat Immunol 19, 1283–1285 (2018). https://doi.org/10.1038/s41590-018-0263-3

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