Chemogenetic profiling can reveal genetic determinants that coordinate phenotypic responses to therapeutics, along with predicting potential pathways of resistance. A new analytical method for evaluating chemogenetic profiles reveals contributions from death-regulatory genes.
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Gelles, J.D., Chipuk, J.E. The death gaze of MEDUSA. Nat Chem Biol (2024). https://doi.org/10.1038/s41589-024-01594-5
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DOI: https://doi.org/10.1038/s41589-024-01594-5
