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MYOSITIS

Targeting necroptosis for the treatment of myositis

Nature Reviews Rheumatology volume 18, pages 307–308 (2022)Cite this article

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New evidence implicates necroptosis in muscle fibre damage in idiopathic inflammatory myopathies, but is it too soon to suggest that interfering with this cell-death pathway could offer a novel therapeutic strategy?

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Fig. 1: Mechanisms of muscle cell death and weakness in myositis.

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Acknowledgements

The authors’ work is supported by funding from Cure JM Foundation and The Myositis Association.

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  1. Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, Binghamton University, Binghamton, NY, USA

    Kanneboyina Nagaraju & Melissa Morales

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  1. Kanneboyina Nagaraju
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  2. Melissa Morales
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Correspondence to Kanneboyina Nagaraju.

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The authors declare no competing interests.

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Nagaraju, K., Morales, M. Targeting necroptosis for the treatment of myositis. Nat Rev Rheumatol 18, 307–308 (2022). https://doi.org/10.1038/s41584-022-00775-7

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