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  • Focus Review
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Synthesis of sequence-controlled polymers via sequential multicomponent reactions and interconvertible hybrid copolymerizations

Polymer Journal volume 52, pages 33–43 (2020)Cite this article

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Abstract

Synthesizing artificial polymers with precise sequence structures, such as their biological analogues, is a serious challenge and of great importance in polymer science. Recently, step-growth polymerization and chain growth polymerization have been the main synthesis methods for preparing artificial sequence-regulated polymers. However, it is difficult to obtain sequence-controlled polymers with sufficient molecular diversity via step-growth polymerization; on the other hand, chain-growth polymerization generally requires laborious repetitive monomer feeding. In this focus review, the sequential multicomponent reactions for preparing periodic sequence-controlled polymers with sufficient molecular diversity and complexity and the interconvertible hybrid copolymerizations producing hybrid multiblock copolymers rapidly in one pot are highlighted.

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Acknowledgements

We acknowledge support from the National Key R&D Program of China (2017YFA0205601), the National Natural Science Funds for Distinguished Young Scholars (21525420, 51625305), the National Natural Science Foundation of China (21774113 and 21801234), and the project funded by the China Postdoctoral Science Foundation.

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  1. CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, 230026, Anhui, China

    Lei Xia, Ze Zhang & Ye-Zi You

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Xia, L., Zhang, Z. & You, YZ. Synthesis of sequence-controlled polymers via sequential multicomponent reactions and interconvertible hybrid copolymerizations. Polym J 52, 33–43 (2020). https://doi.org/10.1038/s41428-019-0266-4

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