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Parvovirus B19 infection in adult patients after allogeneic stem cell transplantation: our experience of five cases and literature review

Bone Marrow Transplantation volume 55, pages 653–656 (2020)Cite this article

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To the Editor

Parvovirus B19 (B19V) typically infects healthy children and manifests as erythema; it sometimes also infects healthy adults, causing arthralgia [1]. Furthermore, in immunocompromised hosts, including solid organ transplant (SOT) or hematopoietic stem cell transplantation (HSCT) recipients, distinctive clinical manifestations of B19V disease, which results from the primary infection as well as from the reactivation, have been reported in both children and adults [1, 2]. However, the clinical overview of B19V diseases in adults after allogeneic HSCT (allo-HSCT) remains incompletely understood because of the lack of large cohort studies. Here, we examined the clinical manifestations of B19V diseases in adults receiving allo-HSCT. We retrospectively analyzed data on B19V disease among adult patients who underwent allo-HSCT in our hospital.

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Acknowledgements

We thank the medical and nursing staff at Kobe City Hospital Organization, Kobe City Medical Center General Hospital.

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Authors and Affiliations

  1. Department of Hematology, Kobe City Medical Center General Hospital, 2-1-1 Minatojima-minamimachi, Chuo-ku, Kobe, Japan

    Daisuke Katoh, Nobuhiro Hiramoto, Mari Morita, Tomohiro Yabushita, Yoshimitsu Shimomura, Yuichiro Ono, Satoshi Yoshioka, Noboru Yonetani, Akiko Matsushita & Takayuki Ishikawa

  2. Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, 54 Kawaharacho, Shogoin, Sakyo-ku, Kyoto, Japan

    Yotaro Ochi

  3. Department of Pathology, Kobe City Medical Center General Hospital, 2-1-1 Minatojima-minamimachi, Chuo-ku, Kobe, Japan

    Daisuke Yamashita & Yukihiro Imai

  4. Department of Cell Therapy, Foundation for Biomedical Research and Innovation, 2-2, Minatojima-minamimachi, Chuo-ku, Kobe, Japan

    Hisako Hashimoto

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  1. Daisuke Katoh
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Correspondence to Daisuke Katoh.

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Katoh, D., Ochi, Y., Hiramoto, N. et al. Parvovirus B19 infection in adult patients after allogeneic stem cell transplantation: our experience of five cases and literature review. Bone Marrow Transplant 55, 653–656 (2020). https://doi.org/10.1038/s41409-019-0533-1

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