Correction: LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation

Correction to: Oncogene

https://doi.org/10.1038/s41388-018-0352-7.

Unfortunately, an error occured in Fig. 3. The correct Fig. 3 is given below.

Fig. 3: Overexpression of LACTB suppresses CRC cell tumorigenecity in vitro.

A Ectopic LACTB expression in HCT116 and HCT8 cell lines were measured by immunoblot. GAPDH was used as a loading control. B Representative images (left panel) and quantification (right panel) of colony formation assay. The number of colonies with >50 cells was scored after 10-day incubation. C CCK-8 assay was used to determine the proliferation effect of LACTB overexpression on HCT116 and HCT8 cells. D EdU (5-ethynyl-2′-deoxyuridine) assay was conducted to assess the effect of LACTB overexpression on DNA synthesis in HCT116 and HCT8 cells. Representative images and corresponding statistical plots were presented. Scare bar = 20 μm. E, F Flow cytometric analysis of cell cycle and apoptosis. Representative images and corresponding statistical plots were presented. G, H The representative pictures and quantification of migrated and invaded cells. Scare bar = 50 μm. Data were represented as means ± S.D. of at least three independent experiments. *p < 0.05; **p < 0.01; ***p < 0.001.