Abstract
The objective of our study was to investigate differences in the management of men and women treated for hypertension while considering the gender of their physicians. We used the data from the cross-sectional Paris Prevention in General Practice survey, where 59 randomly recruited general practitioners (42 men and 19 women) from the Paris metropolitan area enroled every patient aged 25–79 years taking antihypertensive medication and seen during a 2-week period (520 men and 666 women) in 2005–6. The presence in the medical files of six items recommended for hypertension management (blood pressure measurement, smoking status, cholesterol, creatinine, fasting blood glucose and electrocardiogram) was analysed with mixed models with random intercepts and adjusted for patient and physician characteristics. We found that the presence of all items was lower in the records of female than male patients (3.9 vs. 6.9%, p = 0.01), as was the percentage of items present (58.5 vs. 64.2%, p = 0.003). The latter gender difference was substantially more marked when the physician was a man (69.3 vs. 63.4%, p = 0.0002) rather than a woman (63.5 vs. 61.0%, p = 0.46). Although all guidelines recommend the same management for both genders, the practices of male physicians in hypertension management appear to differ according to patient gender although those of women doctors do not. Male physicians must be made aware of how their gender influences their practices.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 digital issues and online access to articles
$119.00 per year
only $9.92 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
Code availability
The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request.
References
World Health Organization [online]. Global health risks: mortality and burden of disease attributable to selected major risks. World Health Organization; 2009. https://apps.who.int/iris/handle/10665/44203.
GBD 2017 Risk Factor Collaborators. Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet Lond Engl. 2018;392:1923–94.
World Health Organisation [online]. Global action plan for the prevention of non-communicable diseases 2013–20. World Health Organization; 2013. https://apps.who.int/iris/bitstream/handle/10665/94384/9789241506236_eng.pdf;jsessionid=D01D54E2714D4DE473D28A3CA7D15412?sequence=1.
Légifrance [online]. Loi n° 2004-806 du 9 août 2004 relative à la politique de santé publique. Légifrance; 2004. https://www.legifrance.gouv.fr/affichTexte.do?cidTexte=JORFTEXT000000787078&categorieLien=id.
Haute Autorité de Santé [online]. Fiche mémo, prise en charge de l’hypertension artérielle de l’adulte. Haute Autorité de Santé; 2016. https://www.has-sante.fr/portail/upload/docs/application/pdf/2016-10/fiche_memo_hta__mel.pdf.
Williams B, Mancia G, Spiering W, Agabiti Rosei E, Azizi M, Burnier M, et al. 2018 ESC/ESH Guidelines for the management of arterial hypertension. Eur Heart J. 2018;39:3021–104.
Grave G, Gautier A, Gane J, Gabet A, Lacoin F, Olié V. Prevention, screening and management of hypertension in France, the point of view of general practitioners, France, 2019. Bull Epidémiol Hebd. 2020;5:115–23.
Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet Lond Engl. 2012;380:2095–128.
Aouba A, Péquignot F, Le Toullec A, Jougla E. Les causes médicales de décès en France en 2004 et leur évolution 1980–2004. BEH. 2007;35–36:308–14.
Laatikainen T, Critchley J, Vartiainen E, Salomaa V, Ketonen M, Capewell S. Explaining the decline in coronary heart disease mortality in Finland between 1982 and 1997. Am J Epidemiol. 2005;162:764–73.
Ford ES, Ajani UA, Croft JB, Critchley JA, Labarthe DR, Kottke TE, et al. Explaining the decrease in U.S. deaths from coronary disease, 1980-2000. N. Engl J Med. 2007;356:2388–98.
Bots SH, Peters SA, Woodward M. Sex differences in coronary heart disease and stroke mortality: a global assessment of the effect of ageing between 1980 and 2010. BMJ Glob Health. 2017;2:e000298.
Stock EO, Redberg R. Cardiovascular disease in women. Curr Probl Cardiol. 2012;37:450–526.
Delpech R, Ringa V, Falcoff H, Rigal L. Primary prevention of cardiovascular disease: more patient gender-based differences in risk evaluation among male general practitioners. Eur J Prev Cardiol. 2016;23:1831–8.
Naicker K, Liddy C, Singh J, Talijaard M, Hogg W. Quality of cardiovascular disease care in Ontario’s primary care practices: A cross sectional study examining differences in guideline adherence by patient sex. BMC Fam Pr. 2014;15:123.
Hambraeus K, Tydén P, Lindahl B. Time trends and gender differences in prevention guideline adherence and outcome after myocardial infarction: Data from the SWEDEHEART registry. Eur J Prev Cardiol. 2016;23:340–8.
Krähenmann-Müller S, Virgini VS, Blum MR, Da Costa MR, Collet TH, Martin Y, et al. Patient and physician gender concordance in preventive care in university primary care settings. Prev Med. 2014;67:242–7.
Bertakis KD. The influence of gender on the doctor-patient interaction. Patient Educ Couns. 2009;76:356–60.
Journath G, Hellénius M-L, Manhem K, Kjellgren KI, Nilsson PM, Hyper-Q Study Group, Sweden. Association of physician’s sex with risk factor control in treated hypertensive patients from Swedish primary healthcare. J Hypertens. 2008;26:2050–6.
Schieber A-C, Delpierre C, Lepage B, Afrite A, Pascal J, Cases C, et al. Do gender differences affect the doctor-patient interaction during consultations in general practice? Results from the INTERMEDE study. Fam Pr. 2014;31:706–13.
Pickett-Blakely O, Bleich SN, Cooper LA. Patient-physician gender concordance and weight-related counselling of obese patients. Am J Prev Med. 2011;40:616–9.
Gross R, McNeill R, Davis P, Lay-Yee R, Jatrana S, Crampton P. The association of gender concordance and primary care physicians’ perceptions of their patients. Women Health. 2008;48:123–44.
Schmittdiel JA, Traylor A, Uratsu CS, Mangione CM, Ferrara A, Subramanian U. The association of patient-physician gender concordance with cardiovascular disease risk factor control and treatment in diabetes. J Women’s Health. 2009;18:2065–70.
Flocke SA, Gilchrist V. Physician and patient gender concordance and the delivery of comprehensive clinical preventive services. Med Care. 2005;43:486–92.
Rigal L, Saurel-Cubizolles M-J, Falcoff H, Bouyer J, Ringa V. The organization of the health care provider’s practice participation in research: a multilevel analysis. J Clin Epidemiol. 2013;66:426–35.
Haute Autorité de Santé [online]. Prise en charge des patients adultes atteints d’hypertension artérielle essentielle. Haute Autorité de Santé; 2005. https://www.has-sante.fr/upload/docs/application/pdf/2011-09/hta_2005_-_recommandations.pdf.
Pelletier-Fleury N, Le Vaillant M, Hebbrecht G, Boisnault P. Determinants of preventive services in general practice. A multilevel approach in cardiovascular domain and vaccination in France. Health Policy Amst Neth. 2007;81:218–27.
Carrier ER, Schneider E, Pham HH, Bach PB. Association between quality of care and the sociodemographic composition of physicians’ patient panels: a repeat cross-sectional analysis. J Gen Intern Med. 2011;26:987–94.
Christian AH, Mills T, Simpson SL, Mosca L. Quality of cardiovascular disease preventive care and physician/practice characteristics. J Gen Intern Med. 2006;21:231–7.
Tabenkin H, Eaton CB, Roberts MB, Parker DR, McMurray JH, Borkan J. Differences in cardiovascular disease risk factor management in primary care by sex of physician and patient. Ann Fam Med. 2010;8:25–32.
Maserejian NN, Link CL, Lutfey KL, Marceau LD, McKinlay JB. Disparities in Physicians’ interpretations of heart disease symptoms by patient gender: results of a video vignette factorial experiment. J Women’s Health. 2009;18:1661–7.
Melloni C, Berger JS, Wang TY, Gunes F, Stebbins A, Pieper KS, et al. Representation of women in randomized clinical trials of cardiovascular disease prevention. Circ Cardiovasc Qual Outcomes. 2010;3:135–42.
Whelton PK, Carey RM, Aronow WS, Casey DE, Collins KJ, Dennison Himmelfarb C, et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: executive summary: a report of the american college of cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Hypertens Dallas Tex 1979. 2018;71:1269–324.
Del Guidice M. Gender differences in personality and social behavior. In: Wright JD, editor. International encyclopedia of the social and behavioral sciences, 2nd ed. 2015. p. 750–6.
Duru-Bellat ML. L’école des Filles: quelle formation pour quels rôles sociaux? Paris: L’Harmattan; 2004.
Snijders TomAB, Bosker RJ. Standard errors and sample sizes for two-level research. J Educ Stat. 1993;18:237–59.
Acknowledgements
The authors are extremely grateful to all the patients and GPs who took part in this study and the entire Paris Prevention in General Practice team.
Funding
The Paris Prevention in General Practice received financial support from the French National Institute of Health and Medical Research (Inserm), the National Health Insurance Fund for Employees (CNAMTS), the French Health Authority (HAS), the Directorate for Research, Studies, Evaluation and Statistics (Drees), the Interministerial Mission on Research (MIRE), the National Public Health Research Institute (IReSP), the French Institute of Health Prevention and Education (Inpes) and the Fondation de France.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no conflict of interest.
Additional information
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Supplementary information
41371_2020_450_MOESM1_ESM.docx
Supplementary Table 1. Patient gender differences in medical management of hypertension according to their cardiovascular risk level (n=1141)
41371_2020_450_MOESM2_ESM.docx
Supplementary Table 2. Patient gender differences in medical management of hypertension in patients with or without known diabetes (n=1141)
41371_2020_450_MOESM3_ESM.docx
Supplementary Table 3. Patient gender differences in medical management of hypertension according to their blood pressure level (n=1114)
41371_2020_450_MOESM4_ESM.docx
Supplementary Table 4. Patient gender differences in medical management of hypertension according to general practitioners’ gender and patients’ cardiovascular risk level (n=1141)
Rights and permissions
About this article
Cite this article
Patrice, C., Delpech, R., Panjo, H. et al. Differences based on patient gender in the management of hypertension: a multilevel analysis. J Hum Hypertens 35, 1109–1117 (2021). https://doi.org/10.1038/s41371-020-00450-y
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41371-020-00450-y