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Aspirin in the prevention of preeclampsia: the conundrum of how, who and when

Abstract

Aspirin is widely used in preventing early onset preeclampsia in women who are identified as being high risk. Although the benefit of aspirin is increasingly evident and acknowledged, there remains many unanswered questions with regards to its optimal application in pregnancy. The issues mainly centre around the relatively modest risk reduction that is observed with the use of aspirin prophylactically. We aim to explore the reasons behind the conservative rate of benefit and aim to explore factors that are likely to influence the outcomes with the use of aspirin.

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Acknowledgements

We thank Mr Rajeev Wijesekera for his assistance with the design of the illustrations used in this manuscript.

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RS, AH, and AM contributed equally and collaboratively in the literature review, proof reading, and preparation of this manuscript.

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Shanmugalingam, R., Hennessy, A. & Makris, A. Aspirin in the prevention of preeclampsia: the conundrum of how, who and when. J Hum Hypertens 33, 1–9 (2019). https://doi.org/10.1038/s41371-018-0113-7

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