In 664 patients from the French ESPOIR early rheumatoid arthritis (RA) cohort, remission after 6 or 12 months could be predicted from baseline variables in 26.8–51.4% of patients. In addition to young age, six clinical variables included in core datasets predicted remission: tender joint count; swollen joint count; physician's global estimate; patient's global estimate; patient-reported physical function; and pain. Of the six remission criteria applied, four required a formal joint count (ACR–EULAR Boolean criteria; simplified disease activity index; clinical disease activity index; and 28-joint disease activity score) and two did not (routine assessment of patient index data 3 (RAPID3) and a RAPID3 score ≤3 plus 0–1 swollen joints). However, the absence of traditional indicators of poor prognosis in RA did not predict remission.
References
Castrejón, I. et al. Prediction of remission in a French early arthritis cohort by RAPID3 and other core data set measures, but not by the absence of rheumatoid factor, anticitrullinated protein antibodies, or radiographic erosions. J. Rheumatol. http://dx.doi.org/10.3899/jrheum.141586 (2016)
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Barranco, C. ESPOIR predictors of remission in early RA. Nat Rev Rheumatol 12, 314 (2016). https://doi.org/10.1038/nrrheum.2016.77
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DOI: https://doi.org/10.1038/nrrheum.2016.77
