Unmet needs in fracture healing have led investigators to question existing paradigms in the hopes of uncovering overlooked solutions. Such is the case in a recent study showing that introduction of a cartilage construct into a mouse tibial defect induces remarkable healing owing to the transformation of donor chondrocytes into new bone.
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Acknowledgements
The authors are supported by NIH grants P30 AR061307; P50 AR054041; and R01 DE019902.
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Nishitani, K., Schwarz, E. Cartilage transplants hold promise for challenging bone defects. Nat Rev Rheumatol 10, 129–130 (2014). https://doi.org/10.1038/nrrheum.2013.216
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DOI: https://doi.org/10.1038/nrrheum.2013.216