The association of environmental dietary factors and polymorphisms of urate transporters with an increased risk of gout has been well established. Nevertheless, the influence of genetics and diet on serum urate concentrations, and the clinical relevance to individual patients, seems to be limited.
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This paper has been partially granted (9/13) by Asociación de Reumatologos del Hospital de Cruces.
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F. Perez-Ruiz declares that he has acted as a consultant for AstraZeneca, Menarini, Novartis, Metabolex, Pfizer, and SOBI. A. M. Herrero-Beites declares no competing interests.
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Perez-Ruiz, F., Herrero-Beites, A. Environment and genetics in gout: a maze for clinicians?. Nat Rev Rheumatol 10, 8–9 (2014). https://doi.org/10.1038/nrrheum.2013.173
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DOI: https://doi.org/10.1038/nrrheum.2013.173
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