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Assessing bone structure in the prediction of osteoporotic fractures

Measuring bone structure could improve prediction of bone strength, but the clinical feasibility of available imaging technologies is limited. The trabecular bone score—a dual-energy X-ray absorptiometry texture algorithm—has shown promise in fracture prediction in a large cohort study, and might provide a practical means of assessing bone quality.

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Figure 1: The effect of confounding factors on DXA images.

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Link, T. Assessing bone structure in the prediction of osteoporotic fractures. Nat Rev Rheumatol 8, 6–8 (2012). https://doi.org/10.1038/nrrheum.2011.174

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