A team from Maastricht University Medical Centre, Netherlands, analysed the results of temperature threshold testing in 81 patients with small-fibre neuropathies and 81 controls, and identified the most time-efficient protocol for diagnosis. Leaving out heat pain threshold testing and limiting the assessment to patients' abilities to detect changes in warm and cool stimuli in both hands and feet yielded diagnostic sensitivity of 84% and specificity of 93%, and shortened examinations from 90 min to 40 min.
References
Bakkers, M. et al. Optimizing temperature threshold testing in small fiber neuropathy. Muscle Nerve 10.1002/mus.24473
Rights and permissions
About this article
Cite this article
New recommendations for use of temperature threshold testing in the diagnosis of small-fibre neuropathy. Nat Rev Neurol 10, 611 (2014). https://doi.org/10.1038/nrneurol.2014.198
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrneurol.2014.198