Blood-oxygen-level-dependent MRI enables noninvasive assessment of renal deoxyhaemoglobin levels and, therefore, hypoxia. As decreased tissue oxygenation might contribute to acute and chronic kidney disease (CKD), this tool has been examined in patients with CKD. Indeed, the benefits of renin–angiotensin–aldosterone system inhibitors might be partly conferred by increased oxygenation.
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Acknowledgements
The author is partly supported by NIH grants DK73608, DK100081, HL77131 and HL121561.
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Lerman, L. BOLD assessment—effects of RAAS inhibition in CKD. Nat Rev Nephrol 10, 247–248 (2014). https://doi.org/10.1038/nrneph.2014.58
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DOI: https://doi.org/10.1038/nrneph.2014.58
