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Mucosal healing in ulcerative colitis: what constitutes remission?

Patients with ulcerative colitis in clinical remission are increasingly undergoing colonoscopies to determine endoscopic remission. However, the histological evaluation of biopsy samples provides additional criteria to predict which patients are most likely to undergo relapse, so what is the ideal therapeutic end point for patients with ulcerative colitis?

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Figure 1: Large bowel biopsies from two patients with quiescent ulcerative colitis.

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Correspondence to Robert H. Riddell.

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Riddell, R. Mucosal healing in ulcerative colitis: what constitutes remission?. Nat Rev Gastroenterol Hepatol 14, 5–6 (2017). https://doi.org/10.1038/nrgastro.2016.194

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