Abstract
Researchers should embrace differences in genetic background to build richer disease models that more accurately reflect the level of variation in the human population, posits Clement Chow.
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The complex underpinnings of genetic background effects
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Acknowledgements
The author would like to thank Charles Murtaugh, Carl Thummel and Brooke LaFlamme for helpful comments.
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Drosophila Genetic Reference Panel (DGRP)
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Chow, C. Bringing genetic background into focus. Nat Rev Genet 17, 63–64 (2016). https://doi.org/10.1038/nrg.2015.9
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DOI: https://doi.org/10.1038/nrg.2015.9
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