In the PRomPT trial presented at the ESC Congress 2015, 126 patients with a large myocardial infarction were randomly assigned to receive dual-site biventricular pacing or single-site left ventricular pacing from an implanted cardiac resynchronization therapy–defibrillator, or not to have a device implanted. After 18 months of follow-up, the increase in left ventricular end-diastolic volume compared with baseline was not significantly different in the two peri-infarct pacing groups combined (16.7 ± 30.5 ml) compared with in the control group (15.3 ± 28.6 ml; P = 0.92). The researchers conclude that “peri-infarct pacing did not prevent left ventricular remodelling or improve functional or clinical outcomes ... in patients with [a] large first myocardial infarction”.