Researchers designed the TASTE trial to investigate whether routine thrombus aspiration before percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) reduced mortality and adverse events. The investigators enrolled 7,244 patients and have previously reported that thrombus aspiration before PCI did not reduce 30-day all-cause mortality compared with those who underwent PCI only. The 1-year follow-up data have now been presented at the ESC Congress 2014, and show no difference between the two groups in all-cause mortality or in the composite end point of all-cause mortality, rehospitalization for myocardial infarction, and stent thrombosis (8.0% with thrombus aspiration versus 8.5% with PCI only; HR 0.94, 95% CI 0.80–1.11, P = 0.48).