Mass spectrometry advances in single-cell metabolomics enable the discovery of a new biological insight that is not accessible from population-level studies. A new study reveals that single baker's yeast cells provide sufficient material to study chemical and genetic inhibition of glycolysis and identifies metabolic subpopulations that would be invisible in bulk.
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Yanes, O. Playing piñata with single cells. Nat Chem Biol 9, 471–473 (2013). https://doi.org/10.1038/nchembio.1297
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DOI: https://doi.org/10.1038/nchembio.1297
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