Abstract
To examine the relationship between chronic periodontal disease (CPD) and ED, the interview sheet including the CPD self-checklist (CPD score) and the five-item version of the International Index of Erectile Function (IIEF-5) was distributed to 300 adult men who received a comprehensive dental examination. Statistical analyses were performed by the Spearman's rank correlation coefficient and other methods. Statistical significance was accepted at the level of P<0.05. The interview sheets were collected from 88 men (response rate 29.3%, 50.9±16.6 years old). There was a statistically significant correlation between the CPD score and the presence of ED (P=0.0415). The results in the present study suggest that ED is related to the damage caused by endothelial dysfunction and the systematic inflammatory changes associated with CPD. The present study also suggests that dental health is important as a preventive medicine for ED.
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References
Demir O, Akgul K, Akar Z, Cakmak O, Ozdemir I, Bolukbasi A et al. Association between severity of lower urinary tract symptoms, erectile dysfunction and metabolic syndrome. Aging Male 2009; 12: 29–34.
Gorbachinsky I, Akpinar H, Assimos DG . Metabolic syndrome and urologic diseases. Rev Urol 2010; 12: e157–e180.
Aktas BK, Gokkaya CS, Bulut S, Dinek M, Ozden C, Memis A . Impact of metabolic syndrome on erectile dysfunction and lower urinary tract symptoms in benign prostatic hyperplasia patients. Aging Male 2011; 14: 48–52.
Mealey BL, Klokkevold PR . Periodontal medicine. In: Newman MG, Takei HH, Carranza FA, eds Carranza’s Clinical Periodontology 9th edn Philadelphia, PA, USA: W.B. Saunders Company, 2002 pp 229–244.
Kwon YE, Ha JE, Paik DI, Jin BH, Bae KH . The relationship between periodontitis and metabolic syndrome among a Korean nationally representative sample of adults. J Clin Periodontol 2011; 38: 781–786.
López NJ, Quintero A, Casanova PA, Ibieta CI, Baelum V, López R . Effects of periodontal therapy on systemic markers of inflammation in patients with metabolic syndrome: a controlled clinical trial. J Periodontol 2012; 83: 267–278.
Fukui N, Shimazaki Y, Shinagawa T, Yamashita Y . Periodontal Status and metabolic syndrome in middle-aged Japanese. J Periodontol 2012; 83: 1363–1371.
Arbes SJ Jr, Slade GD, Beck JD . Association between extent of periodontal attachment loss and self-reported history of heart attack: An analysis of NHANES III data. J Dent Res 1999; 78: 1777–1782.
Dietrich T, Jimenez M, Krall Kaye EA, Vokonas PS, Garcia RI . Age-dependent associations between chronic periodontitis/edentulism and risk of coronary heart disease. Circulation 2008; 117: 1668–1674.
Higashi Y, Goto C, Jitsuiki D, Umemura T, Nishioka K, Hidaka T et al. Periodontal infection is associated with endothelial dysfunction in healthy subjects and hypertensive patients. Hypertension 2008; 51: 446–453.
Zadik Y, Bechor R, Galor S, Justo D, Heruti RJ . Erectile dysfunction might be associated with chronic periodontal disease: two ends of the cardiovascular spectrum. J Sex Med 2009; 6: 1111–1116.
Sharma A, Pradeep AR, Raju PA . Association between chronic periodontitis and vasculogenic erectile dysfunction. J Periodontol 2011; 82: 1665–1669.
Kamoi H, Numabe Y . Self-check of Periodontitis. Sunashobo. Ltd.: Tokyo Japan, 2002.
Rosen RC, Cappelleri JC, Smith MD, Lipsky J, Pena BM . Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction. Int J Impot Res 1999; 11: 319–326.
Johannes CB, Araujo AB, Feldman HA, Derby CA, Kleinman KP, McKinlay JB . Incidence of erectile dysfunction in men 40 to 69 years old: longitudinal results from the Massachusetts male aging study. J Urol 2000; 163: 460–463.
Maekawa T, Takahashi N, Tabeta K, Aoki Y, Miyashita H, Miyauchi S et al. Chronic oral infection with Porphyromonas gingivalis accelerates atheroma formation by shifting the lipid profile. PLoS One 2011; 6: e20240.
Billups KL . Erectile dysfunction as an early sign of cardiovascular disease. Int J Impot Res 2005; 17: S19–S24.
Tonetti MS, D'Aiuto F, Nibali L, Donald A, Storry C, Parkar M et al. Treatment of periodontitis and endothelial function. N Engl J Med 2007; 356: 911–920.
Acknowledgements
We would like to thank following dentists for their cooperation in the study: Tomofumi Mito, Doctor of Dental Medicine (DMD), Mito Dental Clinic (Suehiro, Asahikawa 071-8133); Hiroshi Nakamura, DMD, Nakamura Dental Clinic (Suehiro, Asahikawa 071-8134), Makoto Shinpo, DMD, Shinpo Dental Clinic (4 Jyo-Dori, Asahikawa 070-0034); Hirofumi Harada, DMD, Harada Dental Clinic (4 Jyo-Dori, Asahikawa 078-8214); Toshiya Shibata, DMD, Shibata Dental Clinic (Syunko, Asahikawa 070-0873); Yuichi Yoshida, DMD, Yoshida Dental Clinic (Toyooka, Asahikawa 078-8237).
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APPENDIX
APPENDIX
CPD self-check sheet13
Judgment standard
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0–9 point: There is little possibility of periodontitis.
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10–30 point: There is a possibility of periodontitis.
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31–70 point: It is necessary to check it in the dentist's office.
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71 points or more: The symptom has advanced considerably. Treatment necessary.
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Matsumoto, S., Matsuda, M., Takekawa, M. et al. Association of ED with chronic periodontal disease. Int J Impot Res 26, 13–15 (2014). https://doi.org/10.1038/ijir.2013.30
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DOI: https://doi.org/10.1038/ijir.2013.30
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