Francastel, C., Schübeler, D., Martin, D. I. K. & Groudine, M. Nuclear compartmentalization and gene activity. Nature Reviews Molecular Cell BiologyNovember (2000). http://www.nature.com/nrm/

Gusella, J. F. & MacDonald, M. E. Unmasking polyglutamine triggers in neurodegenerative disease. Nature Reviews Neuroscience November (2000). http://www.nature.com/nrn/index.html

Nature 5 November. This issue contains an Insight review collection on Ageing. Review articles include: Why do we age? Kirkwood, T. B. L. & Austad, S. N. Genetic pathways that regulate ageing in model organisms. Guarente, L. & Kenyon, C The age of cancer. DePinho, R. A. http://www.nature.com/nature/

Partridge, L. & Barton, N. H. Evolving evolvability. A News and Views article that questions whether the ability of yeast prions to generate variation in growth rate across different environments is an adaptation that facilitates evolution. Nature 28 September (2000). http://www.nature.com/nature/

Cowan, D. Use your neighbour's genes.This News and Views article discusses the sequencing of the genome of Thermoplasma acidophilum and what this reveals about this heat-loving microorganism's evolution. Nature 28 September (2000). http://www.nature.com/nature/

Trainor, P. A. & Krumlauf, R. Patterning the cranial neural crest: hindbrain segmentation and Hox gene plasticity. Nature Reviews Neuroscience November (2000). http://www.nature.com/nrn

Nelson, K. E., Paulsen, I. T., Heidelberg, J. F. & Fraser, C. M. Status of genome projects for nonpathogenic bacteria and archaea. Nature Biotechnology October (2000).  http://www.nature.com/nbt/

Nature Structural Biology November (2000). This issue includes a special supplement on structural genomics with an overview by Steve Burley. http://www.nature.com/nsb

Nestler, E. Genes and addiction. Nature Genetics November (2000) . http://www.nature.com/nG/

Goodman, M. F. & Tippin, B. The expanding polymerase universe. A review about the recent explosion in the number of DNA polymerases that have been discovered in eukaryotes and prokaryotes. Nature Reviews Molecular Cell Biology November (2000). http://www.nature.com/nrm/